东风汽车公司职工幽门螺杆菌感染状况及其相关因素

HP infection status and medical related factors of workers in Dongfeng automobile company

目的调查健康检查人群的幽门旋螺杆菌(helicobacter pylori,HP)HP感染程度及相关因素的调查分析。方法选择东风汽车公司职工共8 501例健康检查人员作为调查对象,采用尿素[14C]呼吸试验检测幽门螺杆菌感染情况,测定体重指数(BMI)、空腹检测血糖(GLU)、甘油三酯(TG)、总胆固醇(TC)。结果企业员工HP总感染率为45.7%,其中男性感染45.8%,女性感染45.6%,男女性别与HP感染率无显著性差异;HP感染是随着的年龄增长而增长,其中≥51岁年龄组的女性HP感染率数高,为55%;从感染程度来看,轻、中、重度感染呈现了下阶梯式分布特征;随着BMI、TG、GLU、TC指标的逐步上升,HP感染率呈现逐步上升趋势;BMI、TG、GLU、TC指标的正常范围组与低于正常范围组之间的HP感染率差距不大,而TC≤2.99 mmol/L以下时,HP感染率明显低;而随着指标的异常升高,HP感染率也明显的升高。结论企业员工的HP感染率较高,其年龄、BMI、TC、GLU均与HP之间存在着相关联系,而TG水平与HP感染率之间无明显关系。

[ Objective ] To investigate the Helicobacter pylori （HP） infection degree and related factors of people who took health examination. [Methods] 8501 workers in Dongfeng automobile company who took health examination were selected as the sub- jects. The HP infection status was detected by urea [ 14C] breath test. The BMI, fasting glucose （GLU）, triglyceride （TG} and total cholesterol （ TC ） were detected. [ Results] The HP total infection rate was 45.7%, among men was 45.8% and women was 45.6%, there was not significant difference between men and women. HP infection rate was increased with the growth of age, the infection rate of 〉151 years old women was 55%. From the point of infection degree, the light, medium and severe infection pres- ented under stepped distribution characteristic. With the increasing of BMI, TG, GLU and TC, the HP infection rate gradually in- creased. The difference of HP infection rate between normal BMI, TG, GLU, TC group and below normal range group was not sta- tistically significant. But when the TC was ≤2.99 mmol/L, the Hp infection rate was significantly low. With the abnormal rise of index, the Hp infection rate also increased significantly. [ Conclusion] The HP infection rate of workers is higher. There is inner link between age, BMI, TC and GLU with HP, but there is not significant difference between TG and HP infection rate.