期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

国产左西孟旦治疗急性心肌梗死合并泵衰竭的疗效观察 被引量：4

Observation of Curative Efficacy of Domestic Levosimendan in Patients with Pump Failure Due to an Acute Myocardial Infarction
下载PDF
导出
摘要 针对急性心肌梗死(AMI)并发泵衰竭患者药物治疗不佳的难点,使用国产新型钙增敏剂左西孟旦治疗,观察药物治疗的临床有效率、心衰恶化或死亡率、超声心动图(UCG)左室射血分数(LVEF)及氨基末端脑钠肽前体(NT-ProBNP)、高敏C-反应蛋白(hs-CRP)的变化,结果表明国产左西孟旦治疗急性心肌梗死合并泵衰竭疗效确切,安全性及患者耐受性良好. Due to the poor efficacy of routine drug therapy in patients with pump failure due to an acute myocar-dial infarction,a domestic new calcium sensitizer levosimendan treatment is researched in this paper. The chan-ges in the clinical effective rate,ultrasonic cardiogram （UCG）and amino terminal brain natriuretic peptide pre-cursor （NT-ProBNP）,allergic C -reactive protein （hs -CRP）are then observed. The results show that do-mestic levosimendan has definite therapeutic effect on acute myocardial infarction with pump failure,which is safe and well tolerated in patients.
作者 张云梅 张宏 丁筱雪 陈浩强 赵冲 赵燕 吴咏昕 庞明杰
机构地区 云南省第一人民医院心血管内科
出处 《昆明理工大学学报（自然科学版）》 CAS 北大核心 2014年第2期74-78,共5页 Journal of Kunming University of Science and Technology(Natural Science)
基金 国家自然科学基金项目(31301456)
关键词 左西孟旦 急性心肌梗死 泵衰竭 疗效 levosimendan acute myocardial infarction pump failure efficacy
分类号 R542.2 [医药卫生—心血管疾病]
  • 相关文献

参考文献12

  • 1Sharma M, Teerlink J R. A rational approach for the treatment of acute heart failure : cmTent strategies and future options [ J J. Current opinion in cardiology, 2004, 19 (3) : 254 -263.
  • 2Kivikko M, Antila S, Eha J, et al. Pharmacodynamics and safety of a new calcium sensitizer, levosimendan, and its metabo- lites during an extended infusion in patients with severe heart failure[J]. The Journal of Clinical Pharmacology, 2002, 42 (1):43-51.
  • 3Husebye T, Eritsland J, MUller C, et al. Levosimendan in acute heart failure following primary percutaneous coronary inter- vention - treated acute ST - elevation myocardial infarction. Results from the LEAF trial: a randomized, placebo - con- trolled study [ J ]. European journal of heart failure, 2013, 15 (5) : 565 - 572.
  • 4Moiseyev V S, Poder P, Andrejevs N, et al. Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventrieular failure due to an acute myoeardial infarction. A randomized, placebo - controlled, double - blind study ( RUS- SLAN) [Jl- European heart journal, 2002, 23(18) : 1422 - 1432.
  • 5王雷,崔亮,魏嘉平,李广平,齐国先,郝玉明,王文志,李慧敏,刘俊,姜东炬,张玉东.静脉注射左西孟旦治疗重度失代偿性心力衰竭患者的疗效分析[J].中华心血管病杂志,2010,38(6):527-530. 被引量：57
  • 6Kerbaul F, Rondelet B, Demester J P, et al. Effects of levosimendan versus dobutamine on pressure load - induced right ven- tricular failure[ Jl. Critical care medicine, 2006, 34( 11 ) : 2814 -2819.
  • 7Sonntag S, Sundberg S, Lehtonen L A, et al. The calcium sensitizer levosimendan improves the function of stunned myocardi- um after percutaneous transluminal coronary angioplasty in acute myocardial ischemia[ J]. Journal of the American College of Cardiology, 2004, 43(12): 2177-2182.
  • 8Caira C, Brasolin B, Maestrini V,et al. 475 Effects of Levosimendan on renal function and renalhemodynamic parameters in patients with acute heart failure[J]. European heart journal Fail Suppl,2007,6:103.
  • 9Mancone M, Pennacchi M, Lucisano L, et al. Hemodynamic improvement following levosimendan treatment in acute myocar- dial infarction complicated by cardiogenic shock patients treated with primaly PCI and IABP[ J]. Journal of the American Col- lege of Cardiology, 2013, 61 (10_S).
  • 10林旭常,张木坤,陈景连.超敏C反应蛋白及载脂蛋白A-1、B-100水平变化在急性心肌梗死诊断中的意义[J].广东医学院学报,2011,29(3):288-289. 被引量：11

二级参考文献14

  • 1Nieminen MS,Bohm M,Cowie MR,et al.Executive summary of the guidelines on the diagnosis and treatment of acute heart failure:the Task Force on Acute Heart Failure of the European Society of Cardiology.Eur Heart J,2005,26:384-416.
  • 2Follath F,Cleland JG,Just H,et al.Efficacy and safety of intravenous levosimendan compared with dubutamine in severe lowoutput heart failure (the LIDO study):a randomised donble-blind trial.Lancet,2002,360:196-202.
  • 3Moiseyev VS,Poder P,Andrejevs N,et al.Safety and efficacy of a novel calcium sensitizer,levosimendan,in patients with left ventricular failure due to an acute myocardial infarction.A randomized,placebo-controlled,double-blind study (RUSSIAN).Eur Heart J,2002,23:1422-1432.
  • 4Cleland JG,Ghosh J,Freemantle N,et al.Clinical trials update and cumulative meta-analyses from the American College of Cardiology:WATCH,SCD-HeFT,DINAMIT,CASINO,INSPIRE,STRATUS-US,RlO-Lipids and cardiac resynchronisation therapy in heart failure.Eur J Heart Fail,2004,6:501-508.
  • 5McMurray JJ,Pfeffer MA.Heart failure.Lancet,2005,365:1877-1889.
  • 6Lloyd-Jones DM,Larsen MG,Leip EP,et al.Lifetime risk for developing congestive heart failure:the Framingham Heart Study.Circulation,2002,106:3068-3072.
  • 7Sharma M,Tserlink JR.A rational approach for the treatment of acute heart failure:current strategies and future options.Curr Opin Cardiol,2004,19:254-263.
  • 8Dec GW.Acute decompensated heart failure:the shrinking role of inotropic therapy.J Am Coil Cardiol,2005,46:65-67.
  • 9Nieminen MS,Akkila J,Hasenfuss G,et al.Hemodynamic and neurohumoral effects of continuous infusion of levesimendan in patients with congestive heart failure.J Am Coll Cardiol,2000,36:1903-1912.
  • 10Nijhawan N,Nicolosi AC,Montgomery MW,et al.Levosimendan enhances cardia performance after cardiopulmonary bypass:a prospective,randomized placebo-controlled trial.J Cardiovasc Pharmacol,1999,34:219-228.

共引文献66

同被引文献53

  • 1刘彤,李立丰,李广平.左西孟旦在急性失代偿心力衰竭治疗中的应用进展[J].中华急诊医学杂志,2006,15(6):571-573. 被引量：6
  • 2王惠珍,史蕾,高钰琳.广州市省级养老院内老年人抑郁情绪及生活满意度调查[J].护理学报,2007,14(2):5-7. 被引量：57
  • 3汪向东，王希林，马弘，等．心理卫生评定量表手册[M]．北京：中国心理卫生杂志社，1999．
  • 4Blazer D G. Depression in late life : review and commentary[ J]. Journal of Gerontology, 2003, 58 ( 3 ) :249 - 265.
  • 5Small G W. Differential diagnoses and assessment of depression in elderly patients[ J ]. Journal of Clinical Psychiatry, 2009, 70 (12) :e47.
  • 6Steffens D C. A multiplicity of approaches to characterize geriatric depression and its outcomes [ J ]. Current Opinion Psychiatry, 2009, 22(6) :522 -526.
  • 7Fiske A, Wetherell J L, Gatz M. Depression in older adults[ J ]. Annual Review of Clinical Psychology, 2009 (5) :363 -389.
  • 8Djernes J K. Prevalence and predictors of depression in populations of elderly: a review [ J ]. Aeta Psyehiatriea Seandinaviea, 2006, 113(5) :372 -387.
  • 9Chang H H, Tsai S L, Chen C Y, et al. Outcomes of hospitalized elderly patients with geriatric syndrome.report of a communi- ty hospital reform plan in Taiwan[ J]. Archives of Gerontology and Geriatrics, 2010, 50( Suppll ) :$30 -$33.
  • 10Bryant C, Jackson H, Ames D. The role of physical and psychological variables in predicting the outcome of hospitalization in very old adults[J]. Archives of Gerontology and Geriatrics, 2011, 53(2) :146 -151.

引证文献4

二级引证文献27

昆明理工大学学报（自然科学版）
2014年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部