短叶决明的化学成分研究

Chemical Constituents of Cassia leschenaultiana

目的:研究豆科决明属植物短叶决明的化学成分,为扩大药用资源提供依据。方法:采用柱色谱和重结晶方法分离纯化短叶决明的乙醇提取物,运用波谱技术鉴定化合物结构。结果:一共分离得到了7个化合物,经鉴定为大黄素-8-O-β-d-龙胆二糖苷(1)、2-甲氧基大黄酚-8-O-β-d-吡喃葡萄糖苷(2)、豆甾醇-3-O-β-d-吡喃葡萄糖苷(3)、β-谷甾醇(4)、豆甾醇(5)、橙黄决明素(6)、和熊果酸(7)。结论:化合物1、2、3、6、7为首次从该植物中得到。本试验结果可为短叶决明的进一步研究提供依据。

OBJECTIVE： To study the chemical constituents from Cassia leschenaultiana, and to provide basis for expanding medicinal resources. METHODS ： The ethanol extract was isolated and purified by column chromatograph and recrystallization meth- od; the structures were identified by spectrometer. RESULTS： 7 compounds were isolated from C. leschenaultiana, and identified as emodin-8-O-β-d-gentiobioside （1）, 2-methoxy-chrysophano-8-O-β-d-glucopyranoside （ 2 ） , stigmasterol-8-O-β-d-glucopyranoside （3） ,β-sitosterol （4）, stigmasterol （5）, aurantio-obtusin （6） and ursolic acid （7）. CONCLUSIONS： Compounds 1,2,3,6, 7 are isolated from this plant for the first time. The study provide reference for the further study of C. leschenaultiana.