中西医对糖尿病合并痛风的病因病机研究

Chinese and Western Medicine Research on Etiology and Pathogenesis of Diabetic Gout

糖尿病合并痛风是一种严重危害糖尿病患者的慢性疾病,其发病机制从中西医上有不同的认识;中医着重从阴虚津亏,浊毒内生;禀赋不足,脾肾亏虚;素体肥胖,饮食不节;情志不遂,肝气郁结;瘀血内阻,脉络不通等这几个方面进行论述。西医则着重在嘌呤代谢异常、胰岛素抵抗(IR)与TRB3、胰高血糖素样肽-1(GLP-1)、氧化应激、核因子κB(nuclear factor kappa B,NF-κB)方面进行讨论。

Diabetic gout is a diabetic chronic disease which seriously damages the patients with diabetes. The pathogenesis from traditional Chinese and Western medicine has different understandings. Chinese medicine believes the pathogenesis from aspects： Yin deficiency and fluid exhaust, spleen-kidney deficiency, improper diet, liver-Qi stagnation, blood stasis and collaterals obstruction. Western medicine emphasizes the purine metabolism, insulin resistance （ IR ） and TRB3, glucagon peptide 1 （ glp-1 ）, oxidative stress and the nuclear factor kappa B predominate （ nuclear factor kappa B, the nf-kappa B ）.