中药藤草煎治疗成人免疫性血小板减少症缓解抑郁情绪

Traditional Chinese Medicine Rattan Grass Decoction Alleviating Depression of Adult Immune Thrombocytopenia

目的:观察藤草煎治疗成人慢性原发性免疫性血小板减少症及合并抑郁情绪的效果,为临床合理用药提供依据。方法:选择我院门诊及住院治疗的慢性成人原发性免疫性血小板减少症合并抑郁情绪的患者为研究对象,采用Zung抑郁自评量表(SDS)进行抑郁情绪评定。67例患者随机分为2组,均常规给予维生素C及泼尼松治疗,治疗组在此基础上给予中药藤草煎治疗。结果:治疗3个月后,两组患者血小板计数均有明显改善,治疗组总有效率93.8%,对照组总有效率82.9%,治疗组明显优于对照组,差异有统计学意义(P<0.05);治疗组和对照组患者SDS评分治疗前分别为(59.72±6.31)、(61.46±7.45)分,治疗后分别为(42.53±10.06)、(50.37±9.68)分,两组患者SDS评分治疗后均明显降低(P<0.05);且治疗组明显低于对照组,差异有统计学意义(P<0.05)。结论:采用中药藤草煎治疗慢性成人原发性免疫性血小板减少症,疗效肯定,并且可以明显缓解患者的抑郁情绪,值得进一步研究。

Objective：To observe the effect of the Rattan Grass Decoction on adult chronic primary immune thrombocytopenia and merged depression and to provide the basis for clinical rational drug use. Methods： Outpatients and hospitalized patients suffered by adult primary immune thrombocytopenia with chronic depression in our hospital were chosen as the research objects. Zung Depression Self Rating Scale （ SDS ）was used for evaluating depression. 67 patients were randomly divided into 2 groups and both were conventionally given vitamin C and prednisone treatment while patients in treatment group were given extra Chinese Rattan Grass Decoction treatment. Results： 3 months later, the platelet counts of the patients in 2 groups were obviously improved and the total effectiveness of the treatment group reached 93.8% and that of the control group reached 82.9%. The treatment group was better than control group and the difference was statistically significant （ P〈0.05 ）. SDS scores of patients in treatment group and control group before treatment were （ 59.72 ± 6.31 ）and （ 61.46 ± 7.45 ）respectively. After treatment,SDS scores were （ 42.53 ± 10.06 ）and （ 50.37 ± 9.68 ）respectively. SDS scores in 2 groups were significantly lower after treatment （ P〈0.05 ） and the score of the treatment group was significantly lower than that of control group and the difference was statistically significant （ P〈0.05 ）. Conclusion ： Using Chinese medicine Rattan Grass Decoction to treat chronic adult primary immune thrombocytopenia can get curative effect and can obviously relieve the patients＇ depression which deserves further study.