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利巴韦林治疗疑似病毒感染所致小儿轻度胃肠炎伴无热惊厥48例疗效分析

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摘要 目的 探讨利巴韦林治疗疑似病毒感染所致小儿轻度胃肠炎伴无热惊厥的临床疗效.方法 将48例疑似病毒感染所致小儿轻度胃肠炎伴无热惊厥患儿按随机数字表法分为对照组和治疗组,每组24例,两组患儿均给予补液营养支持治疗,微生态制剂改善胃肠道功能,胃黏膜保护剂保护胃肠道功能等综合治疗.治疗组加用利巴韦林10~15 mg/(kg·d)静脉滴注,并根据临床反馈酌情微调用药剂量.比较两组病情恢复情况.结果 治疗组粪便形状恢复正常时间短于对照组[(2.27±0.12)d比(3.84±1.70)d],再次惊厥次数少于对照组[(0.07±0.02)次比(0.37±0.07)次],住院时间也短于对照组[(2.50±0.75)d比(5.64±0.15)d],两组比较差异均有统计学意义(P<0.05).治疗组治疗期间未发生与应用利巴韦林有关的明显不良反应.结论 利巴韦林治疗疑似病毒感染所致轻度小儿胃肠炎伴无热惊厥的疗效显著,可明显缩短病程.
作者 钟凤娣
出处 《中国医师进修杂志》 2014年第12期68-69,共2页 Chinese Journal of Postgraduates of Medicine
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