摘要
目的:观察加味逍遥颗粒对肿瘤患者血清胰岛素样生长因子-1(Insulin-like Growth Factor-1,IGF-1)的影响,探讨血清IGF-1与肿瘤相关性抑郁的关系。方法:采用自身前后对比法,以血清IGF-1水平为观察指标。结果:治疗前后肿瘤相关性抑郁患者血清IGF-1水平下降,P<0.05(P=0.041),具有统计学意义。结论:加味逍遥颗粒能够降低肿瘤患者血清IGF-1水平,IGF-1与肿瘤相关性抑郁呈正相关。
Objective：To observe the effect of modified Xiaoyao granules on the serum IGF-1 of tumor patients , and explore the rela-tionship between tumor related depression and serum IGF-1.Methods：Comparison before-after study, and the level of serum IGF-1 was observed.A total of 64 patients with cancer related depression were given continuous treatment of 2 courses （14 days for a course）.Re-sults：The serum IGF-1 level of cancer-related depression patients before treatment was obviously higher than that of normal small sam -ples;after 28 days treatment , serum IGF-1 level of patients decreased , with statistical significance , P＆lt;0.05 （ P=0.041 ） .Conclu-sion：Modified Xiaoyao granules can reduce IGF-1 level.Verification of IGF-1 and cancer related depression is positively relevant .
出处
《世界中医药》
CAS
2014年第4期443-445,448,共4页
World Chinese Medicine
基金
北京中医药大学自主选题项目(编号:2010JYB22-JS055)
