泸州医学院附属医院2009-2012年口服抗糖尿病药物应用分析

Utilization of oral antidiabetics in the Affiliated Hospital of Luzhou Medical College from 2009to 2012

目的:调查泸州医学院附属医院2009-2012年口服抗糖尿病药物的应用情况和发展趋势。方法:对本院2009-2012年口服抗糖尿病药物的主要品种、用药金额、用药频度(DDDs)和限定日费用等进行统计和分析。结果:本院口服抗糖尿病药物2012年的用药金额和DDDs分别是2009年的1.59倍和1.37倍,呈上升趋势。用药金额构成比居首位的药物类别2009年是双胍类药物,2010-2012年是α-葡萄糖苷酶抑制剂。最常用的口服抗糖尿病药物是二甲双胍、阿卡波糖、格列吡嗪和瑞格列奈。结论:本院口服抗糖尿病药物的临床应用合理,需求量逐年增加。研发安全、有效、依从性好、价格适中的糖尿病治疗药物是发展的必然趋势。

Objective： To investigate the current situation and trend in the utilization of oral antidiabetics in the Affiliated Hospital of Luzhou Medical College from 2009 to 2012. Methods： The main categories, consumption sum, DDDs and defined daily cost （DDC） of oral antidiabetics in the hospital from 2009 to 2012 were collected and analyzed. Results： The consumption sum and DDDs of oral antidiabetics in 2012 were 1.59 and 1.37 constituent ratio of consumption sum of biguanides ranked first of 2010 to 2012. The most frequently used oral antidiabetics were metformin, acarbose, glipizide and repaglinide. Conclusion： The ulilization of oral antidiabetics was generally rational in the hospital, but with a gradual increase year by year. The development of safe, effective, well-compatible and moderately priced antidiabetie drugs was a logical trend.