CD4＋CD25＋调节性T细胞在呼吸系统疾病中的作用研究

The study of CD4＋CD25＋ regulatory T cell in common respiratory diseases

调节性T细胞是一类可以调节其他多种免疫细胞功能的T细胞亚型，具有免疫应答低下和免疫抑制特性，在维持机体免疫耐受和免疫自稳方面具有非重要的作用，其中CD4＋CD25＋凋节性T细胞是最重要也是目前研究最多的调节性T细胞亚型。目前已发现CD4＋CD25＋调节性T细胞的异常与多种疾病的发生、发展及与预后密切相关。就CD4＋CD25＋。调节性T细胞与常见的呼吸系统疾病的关系作一综述。

Regulatory T cell （Treg） can regulate the function of other immunocytes,characterized by immune annergy and immune suppression, have play a fundamental role in maintaining immunologic tolerance and immune homeostasis in vivo,and the CD4＋CD25＋ regulatory T cell is most important and well studied subtype. The abnormity of CD4＋CD25＋ regulatory T cell is closely correlated to the occurrence,development and prognosis of many human diseases. The relationship between CD4＋CD25＋ regulatory T cell and common respiratory diseases will be reviewed in this article.