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肾交感神经消融治疗高血压及其研究进展 被引量:1

Renal sympathetic nerve ablation treatment for hypertension and its research progress
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摘要 肾交感神经的过度激活可能是高血压的产生和维持的关键因素,肾交感神经消融属选择性的去交感神经化治疗,为高血压的治疗提供了新途径,本文对肾交感神经消融治疗高血压的安全性、有效性及其适应症的进一步拓展作一综述。 Excessive activation of renal sympathetic nerves may be a key factor for occurrence and maintenance of hypertension.Renal sympathetic nerve ablation is a selective sympathetic denervation therapy,Which provides neW route for antihypertensive treatment.This article made an overvieW on further expansion of safety,effectiveness and indications of renal sympathetic nerve ablation treatment for hypertension.
作者 王莎 李述峰
出处 《心血管康复医学杂志》 CAS 2014年第2期218-220,共3页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 高血压 交感神经系统 导管消融术 Hypertension Sympathetic nervous system Catheter ablation
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同被引文献12

  • 1Calhoun DA,Jones D,Textor S,et al.Resistant hypertension:diagnosis,evaluation,and treatment[J].Circulation,2008,51:1403-1419.
  • 2Grasi G.Asesment of sympathetic cardiovascular drive in human hypertension:achievements and perspectives[J].Hypertension,2009,54(4):690-697.
  • 3Atherton DS,Deep NL,Mendelsohn FO.Micro-anatomy of the renal sympathetic nervous system A human postmortem histologic study[J].Clin Anat,2012,25:628-633.
  • 4Symplicity HTN-1 Investigators.Catheter-based renal sympathetic denervation for resistant hypertension:durability of blood pressure reduction out to 24months[J].Hypertension,2011,57:911-917.
  • 5Symplicity HTN-2 Investigators,Esler MD,Krum H,et al.Renalsympathetic denervation in patients with treatment-resistant hypertension(The Symplicity HTN-2Trial):a randomized controlled trial[J].The Lancet,2010,376:1903-1909.
  • 6Persu A,Jin Y,Azizi M,et al.Blood pressure changes after renal denervation at 10 European expert centers[J].J Hum Hypertens,2014,28(3):150-156.
  • 7Gosain P,Garimella PS,Hart PD,et al.Renal sympathetic denervation for treatment of resistant hypertension a systematic review[J].J Clin Hypertens,2013,15:75-84.
  • 8Mahfoud F,Schlaich M,Kindermann I,et al.Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertensiona pilot study[J].Circulation,2011,123:1940-1946.
  • 9周超飞(综述),任艺虹(审校).经皮导管射频消融肾交感神经治疗顽固性高血压的研究进展[J].中国医师杂志,2012,14(2):274-276. 被引量:4
  • 10胡荣,韩玮,刘惠亮.肾脏交感神经射频消融术治疗顽固性高血压的研究进展[J].中华老年心脑血管病杂志,2013,15(1):95-97. 被引量:4

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