龙游县2008年-2012年应征青年HBsAg及ALT检测结果分析

Analysis of test results of HBsAg and ALT in recruited youth in Longyou county from 2008 to 2012

目的分析龙游县近5年来应征青年乙型肝炎病毒表面抗原(HBsAg)阳性率、丙氨酸氨基转移酶(ALT)异常率及变化趋势,了解该县乙肝流行现状和防治工作进展情况,为疾病防治提供科学依据。方法对该县2008年-2012年3351例应征青年HBsAg、ALT的检测结果进行统计分析,并探讨分析引起应征青年ALT异常的相关因素。结果 2008年-2012年应征青年HBsAg阳性率分别为6.79%、5.67%、4.39%、2.90%、2.26%,阳性率呈逐年下降趋势,农村阳性率为5.17%,城镇阳性率为2.58%,农村高于城镇;ALT异常率分别为7.48%、10.14%、10.42%、16.11%、17.17%,异常率呈逐年上升趋势,且异常率HBsAg阴性组高于阳性组,脂肪肝组高于非脂肪肝组,差异有统计学意义。结论随着HBsAg感染的有效控制,脂肪肝对青年群体肝功能的影响日渐突出,需引起大家的高度重视。

Objective To analyze the positive rate of hepatitis B surface antigen（ HBsAg）,abnormal rate of alanine aminotransferase（ ALT） and their change trend in enrolled youth in recent 5 years in Longyou county,and know the current situation and prevention work of hepatitis B in this county,so as to provide scientific basis for disease prevention and control. Methods The test results of HBsAg and ALT of 3351 enrolled young people from 2008 to 2012 in the county were statistically analyzed, and the related factors causing ALT abnormality were discussed. Results The HBsAg positive rates of enrolled youth from 2008 to 2012 were 6. 79%,5. 67%,4. 39%,2. 90% and 2. 26%,declining year by year,and the rural positive rate（ 5. 17%） was higher than that of the urban area（ 2. 58%）; While the ALT abnormal rates were 7. 48%,10. 14%,10. 42%,16. 11% and 17. 17%,on an upward trend. The abnormal rate of ALT in HBsAg negative group was higher than that in HBsAg positive group,and that in the fatty liver group was higher than non-fatty liver group. The differences had statistical significance. Conclusion With the effective control of HBsAg infection,impact of fatty liver on the liver function of the youth group is increasing,which needs to pay more attention.