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PLA2R1研究进展 被引量:1

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摘要 磷脂酶A2(phospholipase A2,PLA2)是一类能够催化脂蛋白和细胞膜上的甘油磷脂二位酰基酯键,水解形成包括花生四烯酸在内的游离脂肪酸和溶血磷脂的酶族[1]。到目前为止,至少已报道了19种不同的PLA2[2]。根据其催化活性对钙离子的需要程度。
机构地区 泸州医学院
出处 《现代临床医学》 2014年第2期96-99,共4页 Journal of Modern Clinical Medicine
基金 国家自然科学基金(No.81101679)
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参考文献29

  • 1Six DA, Dennis EA. The expanding superfamily of phospholipase A2 enzymes: classification and characterization [J]. Biochim Biophys Acta, 2000, 1488(1 - 2) : 1 - 19.
  • 2Akiba S, Sato T. Cellular function of calcium - independent phospholipase A2 [J]. Biol Pharm Bull, 2004, 27 ( 8): 1174 -1178.
  • 3Kovanen PT, Pentikainen MO. Secretory group II phospholipase a2 a newly recognized Acute - Phase reactant with a role in atherogenesis [J]. Circ Res, 2000, 86 ( 6) : 610 -612.
  • 4Hanasaki K, Arita H. Biological and pathological functions of phospholipase A2 receptor[J]. Arch Biochem Biophys, 1999, 372(2): 215 -223.
  • 5Ancian P, Lambeau G, Mattei M G, et al. The human 180 - kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization [J]. J BioI Chern, 1995, 270 ( 15) : 8963 -8970.
  • 6Zvaritch E, Lambeau G, Lazdunski M. Endocytic properties of the m - type 180 - kDa receptor for secretory phospholipases a [J]. J BioI Chern, 1996, 271 (1) : 250 - 257.
  • 7Acosta JC, 0' loghlen A, Banito A, et al. Chemokine signaling via the CXCR2 receptor reinforces senescence [J] . Cell, 2008, 133 (6): 1006 - 1018.
  • 8Augert A, Payre C, De Launoit Y, et al. The M - type receptor PLA2R regulates senescence through the p53 pathway [J]. EMBO Rep, 2009, 10 ( 3) : 271 - 277.
  • 9Fonteh AN, Atsumi G, Laporte T, et al. Secretory phospholipase A2 receptor - mediated activation of cytosolic phospholipase A2 in murine bone marrow - derived mast cells [J]. J Immunol, 2000,165(5): 2773 -2782.
  • 10Muralikrishna AR, Hatcher JF. Phospholipase a2, reactive Oxygen species, and lipid peroxidation in cerebral ischemia [J]. Free Radic Biol Med, 2006, 40 (3) : 376 - 387.

同被引文献24

  • 1Kessentini - Zouari R, Jebali J, Taboubi S, et al. CC - PLA2 - 1 and CC - PLA2 - 2, two Cerastes cerastes venom - derived phos- pholipases A2, inhibit angiogenesis both in vitro and in vivo [ J ]. Lab Invest, 2010, 90(4) : 510 -519.
  • 2Yagami T, Yamamoto Y, Okamura N, et al. L - type voltage - dependent calcium channel is involved in the snake venom group I A secretory phospholipase A2 -induced neuronal apoptosis [ J ]. Neurotoxicology, 2013, 35 : 146 - 153.
  • 3Yagami T, Yamamoto Y, Koma H. The role of secretory phospho- lipase A(2) in the central nervous system and neurological disea- ses[J]. Mol Neurobiol, 2014, 49(2) : 863 -876.
  • 4DeCoster MA. Group NI secreted phospholipase A2 causes apopto- sis in rat primary cortical neuronal cultures[ J]. Brain Res, 2003, 988(1/2) : 20 -28.
  • 5Nyegaard S, Novakovic VA, Rasmussen JT, et al. Lactadherin in- hibits secretory phospholipase A2 activity on pre - apoptotic leuke- mia cells[J]. PLoS One, 2013, 8(10) : e77143.
  • 6Toyama DO, Gaeta HH, de Pinho MV, et al. An evaluation of 3 - rh- amnosylquercetin, a glycosylated form of quereetin, against the myotoxic and edematogenie effects of sPLA 2 from Crotalus durissus terrifieus[ J]. Biomed Res Int, 2014, 2014: 341270.
  • 7Murakami M, Taketomi Y, Sato H, et al. Secreted phospholipase A2 revisited[J]. J Bioehem, 2011, 150(3) : 233 -255.
  • 8Murakami M, Lambean G. Emerging roles of secreted phospho- lipase A(2) enzymes: an update[J]. Biochimie, 2013, 95( 1 ) : 43 - 50.
  • 9Vulfius CA, Kasheverov IE, Starkov VG, et al. Inhibition of nico- tinic acetylcholine receptors, a novel facet in the pleiotropic activi- ties of snake venom phospholipases A2 [ J ]. PLoS One, 2014, 9 (12) : e115428.
  • 10Shiyu S, Zhiyu L, Mao Y, et al. Polydatin up - regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro[ J ]. B MC Cell Bial, 2011, 12: 31.

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