摘要
Dear Editor,Here,we report the risk factors for severe hand-foot-mouth disease(HFMD)determined by our case-controlstudy.Our findings could help disease prevention and in-tervention initiatives.Patients with severe HFMD displayfatal clinical manifestations with sequelae,requiring≥7days of hospitalization.A tota1 of 249 severe cases treat-ed at Yuxi Children’s Hospital were included in the
Dear Editor,Here,we report the risk factors for severe hand-footmouth disease (HFMD) determined by our case-control study.Our findings could help disease prevention and intervention initiatives.Patients with severe HFMD display fatal clinical manifestations with sequelae,requiring ≥ 7days of hospitalization.A tota 1 of 249 severe cases treated at Yuxi Children's Hospital were included in the case group,and 512 common cases were included in the control group.The demographics and characteristics of these patients,including disease course,medical treatment,and virus type,were assessed.Statistical analyses were conducted using SPSS (version 19.0) software.Based on our research,six independent variables,including age,residence,pathogen,type of hospital first visited,respiratory infection 1 month prior,and contact with confirmed cases 1 week prior,are identified as the risk factors for severe hand-foot-mouth disease.