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AD患者血清中L-谷氨酰胺、溶血磷脂酰胆碱和棕榈酰胺HPLC-MS测定 被引量:1

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摘要 近年来寻找探索一种或几种特异、敏感的生物标志物,早期诊断阿尔茨海默病(Alzheimerdisease,AD),及时干预和治疗,使其不发生或延缓发生受到国内外学者重视。本课题组在采用超高效液相色谱-四级杆-飞行时间串联质谱仪研究筛选AD患者血清中生物标志物时发现L一谷氨酰胺(Lglutamine,LG)、溶血磷脂酰胆碱(1ysophosphati-dylcholine,LPC)和棕榈酰胺(palmiticamide,PA)与对照组有显著性差异。
出处 《中国公共卫生》 CAS CSCD 北大核心 2014年第5期691-692,共2页 Chinese Journal of Public Health
基金 国家自然科学基金(81273193)
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