头孢噻肟钠联合左氧氟沙星腹腔灌注治疗肝硬化腹水并发细菌性腹膜炎的临床研究

Clinical studies of cefotaxime sodium in combination with levofloxacin intraperitoneal perfusion in the treatment of cirrhosis ascites complicated with bacterial peritonitis

目的研究头孢噻肟钠联合左氧氟沙星腹腔灌注治疗肝硬化腹水并发细菌性腹膜炎的治疗效果。方法将82例肝硬化腹水并发细菌性腹膜炎的患者随机分为对照组与治疗组,对照组患者给予常规的内科治疗,治疗组患者在一定的常规治疗基础上还进行腹腔灌注头孢噻肟钠(凯福隆,华北制药河北华民药业有限责任公司)和左氧氟沙星。观察两组患者接受治疗后的疗效并进行比较分析。结果对照组的总有效率为73.1%,而治疗组的总有效率为90.2%,治疗组的治疗效果明显高于对照组,两组的比较差异具有统计学意义,P<0.05。结论头孢噻肟钠联合左氧氟沙星腹腔灌注治疗肝硬化腹水并发细菌性腹膜炎的治疗效果显著,可以作为临床上治疗肝硬化腹水并发细菌性腹膜炎的治疗参考。

Objective To learn the therapeutic effect of cefotaxime sodium in combination with levofloxacin intraperitoneal perfusion in the treatment of cirrhosis ascites complicated with bacterial peritonitis. Methods 82 cases of liver cirrhosis ascites complicated with bacterial peritonitis patients were randomly divided into control group and treatment group. The control group got the conventional medical treatment. The treatment group patients got the certain routine therapy and abdominal cavity perfusion of cefotaxime sodium and levofloxacin. Observe the curative effect of two groups’patients after treatment and analysis them. Results The total effective rate of control group was 73.1% , and the total effective rate of treatment group was 90.2%. The therapeutic effect of treatment group was obviously higher than that of control group and comparison of the two groups statistically significant difference, P＆lt;0.05. Conclusion The treatment effect of cefotaxime sodium in combination with levofloxacin intraperitoneal perfusion in the treatment of cirrhosis ascites complicated with bacterial peritonitis is remarkable, and it can be used as a clinical treatment for reference.