基于证候要素挖掘的更年期抑郁症临床特点与病机分析

Analysis of Pathogenesis and Clinical Characteristics of Climacteric Depression Based on Syndrome Elements

目的:探讨更年期抑郁症患者的基本证候要素,在此基础上探讨其临床特点与基本病机,为更年期情感障碍的防治提供思路。方法:临床采集更年期抑郁症患者的相关信息,挖掘基本证候要素,运用统计学方法探讨不同性别疾病证候要素的差异。结果:女性更年期抑郁症的患病率明显高于男性;火热为男性更年期抑郁症患者的主要病性证候要素,阴虚为女性更年期抑郁症患者的主要病性证候要素,心、肝、肾为病变的核心脏腑。结论:更年期抑郁症的防治,需要在"宣阳开郁"基本治法基础上参考性别因素和病机特点。

Objective：To explore the syndrome elements of climacteric depression and further discuss the ba- sic pathogenesis and clinical characteristics for preventing and treating the disease. Methods：Through gath- ering the information of patients with climacteric depression and exploring its syndrome elements ,the differ- ences between male and female patients are discussed by using statistics method. Results：The occurrence of female climacteric depression is significantly higher than the male. Fire and heat are the dominating syn- drome elements of male patients,while Yin deficiency is the dominating syndrome elements of female pa- tients. Heart,liver and kidney are the core of pathological viscera. Conclusion：To prevent climacteric de- pression ,gender difference and pathogenesis should be considered.