卵巢Sertoli-Leydig细胞瘤临床病理分析

Clinicopathological Analysis of Sertoli-Leydig Cell Tumor of Ovary

目的探讨卵巢Sertoli-Leydig细胞瘤的临床病理学特征。方法对卵巢Sertoli-Leydig细胞瘤进行临床资料、组织病理和免疫表型观察,并复习相关文献。结果卵巢Sertoli-Leydig细胞瘤是一种非常少见的性索-间质肿瘤,特征是出现不同比例和不同分化水平的Sertoli细胞、Leydig细胞和(或)纤维母细胞。免疫组化:Inhibin(+)、VIM(+)。结论卵巢Sertoli-Leydig细胞瘤是一种形态学表现多样的少见肿瘤,诊断主要依据病理形态学特征,免疫组化对诊断可起一定的辅助作用。

Objective To explore the clinicopathological features of Sertoli-Leydig cell tumor of ovary. Methods The clinical data,histopathological examination and immunohistochemical examination of Sertoli-Leydig cell tumor of ovary were observed,and the relevant literatures were reviewed. Results Sertoli-Leydig cell tumor of ovary was a kind of rare sex cord-stromal tumor. The sertoil cells,leydig cells and（or）fibroblast demonstrate were observed in the various sizes and levels. Immunohistochemical features：Inhibin（ ＋ ）,VIM（ ＋ ）. Conclusion Sertoli-Leydig cell tumor of ovary is a kind of rare tumor. The diagnosis mostly depends on the clinic symptoms and histological fea-tures,the immunohistochemistry can be helpful for the diagnosis.