摘要
Organ transplantation has been the only treatment for end-stage organ failure patients. With the development of organ transplantation, more and more patients benefit from it. However, the efficacy of organ transplantation is afflicted with graft rejection, which might lead to serious complications. Induction of antigen-specific immune tolerance has become a promising therapeutic strategy for graft rejection. This strategy could be achieved by application of regulatory T cells.
Organ transplantation has been the only treatment for end-stage organ failure patients. With the development of organ transplantation, more and more patients benefit from it. However, the efficacy of organ transplantation is afflicted with graft rejection, which might lead to serious complications. Induction of antigen-specific immune tolerance has become a promising therapeutic strategy for graft rejection. This strategy could be achieved by application of regulatory T cells.
基金
supported by the Major International(Regional) Joint Research Project of Ministry of Science and Technology of China(No.2008DFA31140/2010DFA32260)
National Science and technology support program(No.2011BAI11B22)
The National Natural Science Foundation of China(No.81370230)
