三阴乳腺癌相关性因素研究进展

Research development of triple negative breast cancer correlatile factors

三阴乳腺癌(triple-negative breast cancer,TNBC)即雌激素受体(ER)、孕激素受体(PR)、人表皮生长因子受体2(HER-2)均为阴性的乳腺癌。是一种特殊类型的乳腺癌,具有独特的生物学行为和临床特征,预后差。对三阴乳腺癌相关性因素的深入研究,将有助于该病的预防、早期诊断、判断疾病的进展和指导治疗。

Triple - negative breast cancer（TNBC） is defined as lack of estrogen receptor（ER） , progesterone receptor （ PR ） and human epidermal growth factor receptor - 2 （ HER - 2） expression, it is a subtype of tumor with distinct clin- ical and pathologic features and poor prognosis. A deeper insight into the correlative factors of TNBC may lead to con- tribute to the prevention of disease,early diagnosis,judge the progress of the disease and guiding treatment.