胃癌根治术后腹腔感染的相关影响因素分析

Related influencing factors for abdominal infections after radical resection of gastric cancer

目的分析胃癌根治术后腹腔淋巴漏并腹腔感染的相关影响因素,探究预防对策。方法对医院2005年1月-2012年12月收治的691例行胃癌根治术的患者进行回顾性分析,将确诊的9例术后腹腔淋巴漏并腹腔感染患者纳入研究组,并将其余682例患者纳入对照组,将两组患者临床指征进行对比,分析感染的影响因素;采用SPSS13.0软件进行统计分析,计数资料采用χ2检验,计量资料采用t检验,对影响胃癌根治术后腹腔淋巴漏并腹腔感染的因素进行logistic回归分析。结果 2005年1月-2012年12月有691例胃癌患者行胃癌根治术治疗,共确诊9例术后腹腔淋巴漏并腹腔感染患者,感染率为1.3%;多因素回归分析发现,贫血、肿瘤TNMⅢ期、行D3根除术是影响胃癌根治术后腹腔淋巴漏并腹腔感染的独立危险因素(P<0.05)。结论贫血、肿瘤TNMⅢ期、行D3根除术是影响胃癌根治术后腹腔淋巴漏并腹腔感染的独立危险因素,应及时纠正患者原发症状,仔细谨慎行淋巴结清扫,以降低该并发症发生率,改善其预后。

OBJECTIVE To analyze the related influencing factors for abdominal lymphorrhagia complicated with abdominal infections and explore the prevention countermeasures.METHODS A total of 691patients,who underwent the radical resection of gastric cancer in the hospital from Jan 2005to Dec 2012,were retrospectively analyzed, then 9cases with confirmed postoperative abdominal lymphorrhagia complicated with abdominal infections were assigned as the study group,while the rest of 682patients were included in the control group,the clinical symptoms were compared between the two groups of patients,the influencing factors for infections were analyzed,the statistical analysis was performed with the use of SPSS 13.0software,the count data were analyzed by means of the chi-square test,the measurement data were analyzed with the use of t-test,and the logistic regression analysis was performed for the related factors for abdominal lymphorrhagia complicated with abdominal infections after the radical resection of gastric cancer.RESULTS Of the 691gastric cancer patients undergoing the radical gastrectomy from Jan 2005to Dec 2012,totally 9cases were confirmed with postoperative abdominal lymphorrhagia complicated with abdominal infections with the infection rate of 1.3%.The multivariate regression analysis indicated that the anemia,tumor TNM stageⅢ,and D3radical resection were the independent risk factors for the postoperative abdominal lymphorrhagia complicated with abdominal infections（P＆lt;0.05）.CONCLUSION The anemia,tumor TNM stageⅢ,and D3radical resection are the independent risk factors for the abdominal lymphorrhagia complicated with abdominal infections after the radical resection of gastric cancer;it is necessary to treat the primary symptoms in a timely manner and carefully perform the lymph node dissection so as to reduce the incidence of the complication and improve the prognosis.