热带爪蟾(Xenopus tropicalis)胚胎在生态毒理学中的应用前景

Application of Xenopus tropicalis Embryos in Ecotoxicology

首先介绍了热带爪蟾(Xenopus tropicalis)作为新的模式动物的发展过程以及热带爪蟾基因组学方面的研究进展,概述了非洲爪蟾(X.laevis)胚胎在生态毒理学中的应用。在此基础上,详细讨论了热带爪蟾胚胎在污染物致毒效应和作用机理、毒理学理论和环境样品生态毒性检测等方面的应用现状和前景。最后,简要介绍了目前国内外有关热带爪蟾网站、书籍和养殖等方面的信息资源。

The development of a new model animal, Xenopus tropicalis, and its genome were introduced. Theapplication ofX. laevis embryos in ecotoxicology was reviewed. Based on the introduction above, the presentsituation and future prospect of the application ofX. tropicalis were discussed in details. These applicationsincluded the developmental toxicity test of contaminants, the research of toxicological mechanisms, the theatri-cal research of toxicology and the ecotoxicological test of environmental samples. Finally, information aboutintemet, books and husbandry ofX. tropicalis was introduced in brief.