摘要
目的:探讨阻抗训练对超重/肥胖大学生血清性激素结合球蛋白(SHBG)浓度变化的影响,为进一步揭示阻抗训练预防2型糖尿病的相关机制提供实验依据及数据支持。方法:20名超重/肥胖(BMI≥23kg/m2和25kg/m2)男性大学生随机分为对照组(C组,n=10)和阻抗训练组(RT组,n=10),C组不训练,RT组进行为期12周的阻抗训练。实验前、后,对受试者体成分、血清SHBG,睾酮,游离睾酮(FT)和游离雄激素指数(FAI)的变化进行观察,并进行口服葡萄糖耐受试验。结果:与C组相比,12周抗组训练后RT组体重及BMI指数均未发生显著改变(P>0.05),而脂肪含量显著降低(P<0.05),去脂体重显著升高(P<0.05)。血液指标方面,血清SHBG显著升高(P<0.05),睾酮水平变化不明显(P>0.05),游离睾酮及游离雄激素指数均显著降低(P<0.05)。口服葡萄糖耐受试验结果发现,RT组空腹血糖水平未发生显著变化(P>0.05),而空腹胰岛素水平、葡萄糖、胰岛素曲线下面积及胰岛素抵抗指数均较C组显著降低(P<0.05)。结论:阻抗训练作为2型糖尿病的一种有效干预方式值得在临床上得到推广。阻抗训练后血清胰岛素水平下降,诱发血清SHGB水平的上升,使体内雌/雄激素的相对平衡性得以提高,葡萄糖耐受力及胰岛素抵抗得以改善,该途径可能是阻抗训练预防2型糖尿病的机制之一。
Objective:To observe the effect of resistance training on serum sex hormone-binding globulin (SHBG) of overweight/obese college students, and provide experimental and data support for revealing the mechanism that resistance training prevents/improves type 2 diabe- tes. Methods. 20 overweight/obese male college students were randomly divided into control group (C group, n = 10) and resistance training group (T group, n = 10). Students of T group received 12 weeks of resistance training, while C group participated in no training. Before and after 12 weeks, the body composition, serum SHt~, testosterone, free testosterone, free testos- terone index and oral glucose tolerance testing were performed. Results .. After 12 weeks, com- pared with C group, the body mass and BMI showed no significant change in T group (P〉 0. 05), while, the fat mass decreased significantly (P〈0. 05 ) and the lean body mass increased significantly (P〈0.05). The SHBG of the T group showed significant increase(P〈0. 05), the testosterone showed no significant change (P〉0. 05) ,while the free testosterone and free testosterone index both showed significant decrease (P〈0. 05). The oral glucose tolerance testing found that, compared with C group, the fasting glucose of T group showed no signifi- cant change, while, the fasting insulin, the total area under the glucose and insulin curves, the insulin resistance index all significantly decreased (P〈0.05). Conclusion:Resistance training is an effective strategy that can be widely extended clinically to interfere with the type 2 diabe- tes. The decreased insulin level after 12 weeks resistance training might reduce the increase of the SHGB, and then, this might enhance the balance of female hormone/ male hormone, im- prove the glucose tolerance and insulin resistance, this might be one possible approach for re- sistance training preventing and improving the type 2 diabetes.
出处
《中国体育科技》
CSSCI
北大核心
2014年第3期89-93,112,共6页
China Sport Science and Technology
关键词
阻抗训练
性激素结合球蛋白
肥胖
2型糖尿病
resistance training
sex hormone-binding globulin
obese
type 2 diabetes