门静脉主干内径与肝硬化分级及肝性脑病的关系

Relationships of portal vein diameter with Child-Pugh classification of liver cirrhosis and hepatic encephalopathy

目的探讨肝硬化患者门静脉主干内径与肝功能Child-Pugh分级及肝性脑病的关系。方法 106例肝硬化患者,肝脏彩超检查门静脉主干内径,采用Child-Pugh分级标准进行肝功能分级,分析患者门静脉主干内径与肝功能ChildPugh分级以及肝性脑病程度间的相关性。结果肝硬化患者门静脉主干内径与肝功能Child-Pugh分级无相关性,但随患者肝脏储备功能减退,肝性脑病发生率增加(P<0.01);肝硬化合并肝性脑病患者门静脉主干内径较无肝性脑病者增宽(P<0.05),但不同程度肝性脑病患者间门静脉主干内径比较差异无统计学意义(P>0.05)。结论根据门静脉主干内径可预测肝硬化患者肝性脑病发生的可能性。

Objective To investigate the relationships of the diameter of portal vein with Child-Pugh classification of liver cirrhosis and hepatic encephalopathy. Methods A total of 106 patients with liver cirrhosis were measured the diameters of portal vein by liver ultrasonic inspection. Child-Pugh classification was used for classifying liver function. The relationships of the diameter of portal vein with Child-Pugh classification and hepatic encephalopathy were analyzed. Results The diameter of portal vein had no correlation with Child-Pugh classification in patients with liver cirrhosis. With the decrease of liver reserve function, the incidence of hepatic encephalopathy increased （P〈0.01）. The diameter of portal vein increased in patients with hepatic encephalopathy compared with the patients without hepatic encephalopathy （P〈0.05）, while there was no significant difference in the diameter of portal vein in the different degrees of hepatic encephalopathy. Conclusions The diameter of portal vein can be used to predict the development of hepatic encephalopathy in patients with liver cirrhosis.