硫氧还蛋白还原酶在肺结核与肺癌患者血浆中表达的对比分析

Comparative Analysis of the Expression of Thioredoxin Reductase in the Plasma of Patients with Pulmonary Tuberculosis and Lung Cancer

目的探索异常增生标志物硫氧还蛋白还原酶(TR)在肺结核与肺癌患者血浆中的表达水平及其临床意义。方法采用分光光度法检测肺癌、肺结核和健康对照各100例志愿者血浆中异常增生标志物TR的表达水平,并进行对比分析。结果 TR的表达水平肺癌组明显高于肺结核组(P<0.01),肺结核组明显高于健康组(P<0.01)。结论 TR对肺结核病人罹患肺癌具有预警意义,在肺结核患者的治疗过程中具有指导意义。

Objective To explore the levels and clinical significance of abnormal proliferation marker ex-pression of thioredoxin reductase （ TR） in the plasma of patients with lung cancer and tuberculosis .Methods Spectro-photometry was used to detect lung cancer ,tuberculosis and healthy control group with 100 cases in each volunteer plas-ma abnormal proliferation marker expression levels of thioredoxin reductase ,and carries on the contrast analysis .Results Thioredoxin reductase expression levels in lung cancer group were significantly higher than TB （ P〈0 .01 ）;TB was significantly higher than the healthy group （P〉0.01）.Conclusion Thioredoxin reductase tuberculosis patients suffer-ing from lung cancer have early warning sense ,is instructive in the course of treatment of tuberculosis patients .