神经纤维瘤病的CT、MRI表现

CT and MRI diagnosis of neurofibromatosis

目的探讨神经纤维瘤病的CT、MRI表现。方法回顾性分析24例经临床或手术病理证实的神经纤维瘤病患者的CT、MRI表现。结果根据美国国立卫生研究所标准,24例患者,Ⅰ型22例,Ⅱ型2例,其中有4例和2例分别系同一家族成员,分别为母亲和3个儿子及父亲和女儿,且均为Ⅰ型患者,合并皮肤牛奶咖啡斑的12例,皮下多发纤维瘤结节的10例,其中19例行手术确诊。结论神经纤维瘤病的CT、MRI表现有一定特征性,NF1型占大部分,NF2型较少,结合典型临床表现、

Objective To analyze the clinical, CT and MRI features of neurofibromatosis （NF）. Methods The clinical records, CT and/or MRI of 24 patients with NF were evaluated retrospectively. Results Using the diagnostic criteria established by the National Institutes of Health conference, the 24 patients were classified as NF 1 （22） and NF 2 （2） with 6/22 patients of NF 1 belonging to two families. Multiple cutaneous car e au-lait spots were found in 12 and neurofibromas in 10 patients, 19 of whom underwent surgery. Conclusion NF1 is more common with characteristic clinical, CT and MRI features allowing definite diagnosis.