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降钙素原在儿童社区获得性肺炎病原研究中的价值 被引量:5

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摘要 目的:探讨血清降钙素原(PCT)及超敏C-反应蛋白(CRP),血常规白细胞计数(WBC)在儿童社区获得性肺炎(CAP)病原诊断中的价值。方法:将83例社区获得性肺炎患儿分为两组,其中细菌感染性肺炎44例,病毒感染性肺炎39例,收集其血清降钙素原(PCT)、超敏C-反应蛋白(hsCRP)、白细胞计数(WBC)等,比较两组患儿PCT、hsCRP、WBC水平的差异。结果:细菌性肺炎患儿血清PCT、hsCRP和WBC均比病毒性肺炎患儿血清PCT、hsCRP、WBC升高(P<0.05),且PCT的灵敏度及特异度更高(P<0.01),分别为95.45%,74.36%,而hsCRP,WBC灵敏度和特异度在细菌性感染肺炎和病毒感染性肺炎患儿中无显著性差异(P>0.05)。结论:在社区获得性肺炎中,血清PCT是一个较好的诊断或鉴别诊断的指标,比hsCRP更有临床价值。
出处 《陕西医学杂志》 CAS 2014年第5期540-541,590,共3页 Shaanxi Medical Journal
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参考文献7

  • 1中华医学会儿科学分会呼吸学组,《中华儿科杂志》编辑委员会.儿童社区获得性肺炎管理指南:上册(试行)[J].中华儿科杂志,2007 ,2(45) :83-90.
  • 2Jergensen PE, Wang JE, Solberg R,et al. Procalcitonindoes not influence the surface expression of inflammatoryreceptors on whole blood leukocytes [J]. Intensive CareMed,2001,27(2) :430-433.
  • 3Becker KL, Snider R,Nylen ES. Procalcitonin assay insystemic inflammation, infection.and sepsis : clinical utilityand limitations[J]. Crit Care Med,2008,36.3) :941-952.
  • 4Simon L, Gauvin F,Amre DK, et al. Serum procalcitoninand C-reactive protein levels as markers of bacterial infec-tion j a systematic review and meta-analysis[J]. Clin InfectDis,2004,39(2):206-217.
  • 5Giamarellos-Bcurboulis EJ , Grecka P,Poulakou G, et al.Assessment of procalcitonin as a diagnostic marker of un-derlying infection in patients with febrile neutropenia[J].Clin Infect Dis,2004,32(12) : 1718-1725.
  • 6党晓燕,秦勇.重症肺炎患者血清降钙素原检测的临床价值[J].陕西医学杂志,2013,42(2):218-219. 被引量:24
  • 7胡凤华,甘小庄,孙丽萍,崔小岱,任晓旭,郭琳英.儿童肺炎支原体肺炎的血清降钙素原和C-反应蛋白的改变[J].中国医刊,2007,42(6):33-35. 被引量:25

二级参考文献16

  • 1Assicot M,Gendrel H,et al.High serum procalcitonin concentrations in patients with sepsis and infection[J].Lancet,1993,341:515 -518.
  • 2Eberhard OK,Haubitz M,Brunkhorst FM,et al.Usefullness of procalcitonin for differentiation between activity of systemic autoimmune and invasive bacterial infection[J].Arthritis Rheum,1997,40:1250-1256.
  • 3Hatzistilianou M,Hitoglou S,Gougoustamou D,et al.Serum procalcitonin,adenosine deaminase and its isoenzymes in the aetiological diagnosis of pneumonia in children[J].Int J Immunopathol Pharmacol,2002,15(2):119-127.
  • 4Nylen ES,Snider RH Jr,Thompson KA,et al.Pneumonitis associated hyperprocalcitoninemia[J].Am J Med Sci,1996,321:1218.
  • 5F Moulin,J Raymond,M Lorrot,et al.Procalcitonin in children admitted to hospital with community acquired pneumonia[J].Arch Dis Child,2001,84:332-336.
  • 6Korppi M.Non-specific host response markers in the differentiation between pneumococcal and viral pneumonia:what is the most accurate combination[J] ? Pediatr Int,2004,46 (5):545-550.
  • 7Morozumi M,Hasegawa K,Chiba N,et al.Application of PCR for Mycoplasma pneumoniae detection in children with community-acquired pneumonia[J].Infect Chemother,2004,10 (5):274-279.
  • 8Beghetti M,Rimensberger PC,Kalangos A. Kinetics of procalcitonin,interleukin 6 and C-reactive protein after cardiopulmonary-bypass in children[J].Cardiology in the Young,2003,(02):161-167.
  • 9Hausfater P,Garric S,Ayed SB. Usefulness of procalcitonin as a marker of systemic infection in emergency department patients:a prospective study[J].Clinical Infectious Diseases,2002,(07):895-901.
  • 10Delèvaux I,André M,Colombier M. Can procalcitonin measurement help in differentiating between bacterial infection and other kinds of inflammatory processes[J].Annals of the Rheumatic Diseases,2003,(04):337-340.doi:10.1136/ard.62.4.337.

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