急性心肌梗死患者高敏心肌肌钙蛋白的变化及意义

Acute myocardial infarction in high-sensitivity cardiac troponin changes and clinical significance

目的:探讨心肌梗死(AMI)不同时间点高敏心肌肌钙蛋白的变化规律及其临床意义。方法:选择急诊AMI患者164例和正常对照组90例,在AMI患者入院0h,6h,24h,48h及5d分别取血检测血清hs-cTnT、hs-CRP,CK-MB的浓度。结果:AMI血清hs-cTnT、hs-CRP,CK-MB浓度均显著升高,hs-cTnT升高的更早,持续的时间更长。结论:hs-cTnT在诊断AMI时,比hsCRP,CK-MB有更好的敏感性和特异性,有利于AMI的早期诊断和治疗。

Objective：To study the hs-cTnT changes with time and its clinical significance in AMI . Methods ：Collected 164 cases of AMI patients and 90 cases of normal control group ,determined the serum hs-cT-nT ,hs-CRP and CK-MB concentration with AMI patients at 0 h ,6 h ,24 h ,48 h and 5 d .Results ：The serum hs-cTnT ,hs-CRP and CK-MB concentration were significantly rised in AMI ,hs-cTnT rised earlier and last longer . Conclusion ：In the AMI diagnosis ,hs-cTnT has a better sensitivity and specificity than hs-CRP and CK-MB .