期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

生物标志物与心房颤动卒中风险分层 被引量：5

原文传递
导出
摘要 最近大量研究显示,一些生物标志物可增加心房颤动(简称房颤)患者的卒中风险,包括心脏标志物(B型尿钠肽、肌钙蛋白)、肾功能标志物(由肌酐计算的肾小球滤过率和肌酐清除率、半胱氨酸蛋白酶抑制蛋白C)、炎症标志物(白介素-6、C-反应蛋白)和凝血标志物(D-二聚体)等。将生物标志物加入卒中风险评分可能将优化现行的基于CHADS2或CHA2DS2-VASc评分的房颤分层抗凝策略。
作者 陈牧 李毅刚
机构地区 上海交通大学医学院 上海交通大学医学院附属新华医院心血管内科
出处 《中国心脏起搏与心电生理杂志》 2014年第2期161-163,共3页 Chinese Journal of Cardiac Pacing and Electrophysiology
关键词 心血管病学 生物标志物 综述 心房颤动 脑卒中 风险分层 抗凝治疗
分类号 R541.75 [医药卫生—心血管疾病]
  • 相关文献

参考文献32

  • 1Doukky R, Gage H, Nagarajan V, et al. B-type !aatriuretic peptide predicts left atrial appendage thrombus in patients with nonvalvular atrial fibrillation [ J ]. Echocardiography, 2013, 30 ( 8 ) : 889.
  • 2Hijazi Z, Oldgren J, Andersson U, et al. Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation a randomized evaluation of long-term antieoagulation therapy (RE-LY) substudy [ J]. Circulation, 2012, 125 ( 13 ) : 1 605.
  • 3Hijazi Z, Wallentin L, Sieghahn A, et al. NT-proBNP for risk as- sessment in patients with atrial fibrillation: insights from the ARIS- TOTLE trial[J]. J Am Coil Cardiol, 2013, 61(22) : 2 274.
  • 4Purroy F, Surrez-Luis I, Mauri-Capdevila G, et al. N-terminal pro- brain natriuretic peptide level determined at different times identifies transient isehaemic attack patients with atrial fibrillation [ J ]. Eur J Neurol, 2014,21 (4) :679.
  • 5Rodrtguez-Yrfiez M, Arias-Rivas S, Santamaria-Cadavid M, et al. High pre-BNP levels predict the occurrence of atrial fibrillation after eryptogenic stroke [ J ]. Neurology, 2013, 81 ( 5 ) : 444.
  • 6Fujii S, Shibazaki K, Kimura K, et al. A simple score for predic- ting paroxysmal atrial fibrillation in acute isehemie stroke [ J ]. JNeurol Sei, 2013,328( 1 ) :83.
  • 7Longstreth WT, Kronmal RA, Thompson JLP, et al. Amino termi- nal pro-B-type natriuretic peptide, secondary stroke prevention, and choice of antithrembotic therapy [ J ]. Stroke, 2013, 44 ( 3 ) : 714.
  • 8Parwani AS, Boldt LH, Huemer M, et al. Atrial fibrillation-induced cardiac treponin I release[J]. Int J Cardio/, 2013,168(3) :2 734.
  • 9Hijazi Z, Wallentin L, Sieghahn A, et al. High sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin. J Am Coil Cardiol, 2013, [ Epub ahead of print].
  • 10Roldan V, Marin F, Diaz J, et al. High sensitivity cardiac troponin T and interleukin-6 predict adverse cardiovascular events and mortal- ity in antieoagulated patients with atrial fibrillation [ J ]. J Thromb Haemost, 2012, 10(8) : 1 500.

同被引文献37

  • 1曾治宇,王方正,谭琛,张澍,浦介麟.心房颤动与C反应蛋白[J].中国循环杂志,2005,20(3):197-199. 被引量：6
  • 2Inoue H, Nozawa T, Okumura K, et al. Prothrombotic activity is in- creased in patients with nonvalvular atrial fibrillation and risk factor for embolism[J]. Chest, 2004,126(3) :687.
  • 3Nozawa T, Inoue H, Hirai T, et al. D-dimer level influences throm- boembolic events in patients with atrial fibrillation[J]. Int J Cardi- ol, 2006,109(1) :59.
  • 4Fu R, Wu S, Wu P, et al. A Study of blood soluble P-selectin, fi- brinogen, and von Willebrand factor levels in idiopathic and lone at- rial fibrillation[J]. Europace,2011 ,13 (1) :31.
  • 5Wong CX, Abed HS, Molaee P, et al. Pericardial fat is associated with atrial fibrillation severity and ablation outcome [ J]. J Am Coll Cardiol,2011,57(17) :1 745.
  • 6Nakanishi K, Fukuda S, Tanaka A, et al. Peri-atrial epicardial adi- pose tissue is associated with new onset nonvalvular atrial fibrillation [J]. Circ J,2012,76(12) :2 748.
  • 7Lip GY, Nieuwlaat R, Pisters R, et al. Refining clinical risk strati- fication for predicting stroke and thromboembolism in atrial fibrilla- tion using a novel risk factor-based approach: the Euro heart survey on atrial fibrillation[J]. Chest,2010,137(2) :263.
  • 8Nagashima K, Okumura Y, Watanabe I, et al. Association between epicardial adipose tissue volumes on 3-dimensional reconstructed CT images and recurrence of atrial fibrillation after catheter ablation [J]. Circ J,2011,75(11) :2 559.
  • 9Watson T, Shantsila E, Lip GY. Mechanisms of thrombogenesis in atrial fibrillation : Virehow' s trial revisited [ J ]. Lancet, 2009,373 (9658) :155.
  • 10Heppell RM, Berkin KE, McLenachan JM, et al. Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in- non-rheumatic atrial fibrillation[ J]. Heart, 1997,77 ( 5 ) :407.

引证文献5

二级引证文献9

中国心脏起搏与心电生理杂志
2014年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部