影响深静脉置管血液透析患者发生导管功能不良的临床相关因素分析

Related factors of influencing deep vein indwelling catheter dysfunction in hemodialysis patients： a clinical analysis

目的分析影响深静脉置管血液透析患者发生导管功能不良的临床相关因素。方法选取深静脉置管血液透析患者37例，根据在5个月内是否出现导管功能不良（连续3次透析血流量低于180ml／min，需要调整体位、反接透析管路、溶栓治疗等干预措施），将其分为通畅组和非通畅组，比较两组患者的一般资料及生化指标。结果通畅组28例，非通畅组9例，两组年龄、糖尿病所占比例、血小板计数、低密度脂蛋白胆固醇、白蛋白比较差异无统计学意义（P〉0．05）。通畅组血红蛋白显著低于非通畅组[（90．1±13．8）g/L比（108．3±11．6）g／L]，差异有统计学意义（P〈0．05）。结论血红蛋白是影响深静脉置管血液透析患者发生导管功能不良的临床相关因素。

Objective To analyze the related factors of influencing deep vein indwelling catheter dysfunction in hemodialysis patients. Methods A total of 37 cases with deep vein indwelling catheter in hemodialysis patients were selected. They were divided into patent group and blocked group according to the appearance of catheter dysfunction （hemodialysis blood flow less than three times 180 ml/min, adjustment of body position, inversion of tube connection during hemodialysis, requirement of thrombolytic therapy and so on） in 5 months. The common data and biochemical indicator were compared between two groups. Results Patent group had 28 cases, and blocked group had 9 cases. There was no significant difference in age, diabetes mellitus ratio, platelet, low density lipoprotein cholesterol and albumin between two groups （P 〉 0.05）. Hemoglobin in patent group was lower than that in blocked group [（90.1 ± 13.8） g/L vs. （108.3 ± 11.6） g/L ], and there was significant difference（P 〈 0.05 ）. Conclusion Hemoglobin is the correlated factor that effects deep vein indwelling catheter dysfunction after hemodialysis.