热消融治疗调节机体抗肿瘤免疫研究进展

Advances in thermal ablation therapy for regulating anti-tumor immunity

近年来影像引导下的热消融技术在肝、肾等肿瘤的治疗中发挥了重要的作用。局部热消融技术能够在一定程度上激活机体的抗肿瘤免疫,是真正意义上的体内肿瘤疫苗,但其诱发的免疫反应尚不足以完全消灭肿瘤或长期发挥预防肿瘤复发,因此与其他免疫调节手段同时应用的联合疗法可能发挥更有效的作用。

Image-guided thermal ablation technique plays an important role in treatment of hepatic and renal tumors. Thermal ablation technique can activate the anti-tumor immunity in vivo. However, the immune response of patients to them cannot completely eliminate the tumor or prevent its relapse. Thermal ablation should therefore be applied in combination with other immune-regulating therapies in order to bring its effect into full play.