不同麻醉方法人工流产镇痛效果比较

Propofol Combined of Lidocaine and Atropine for Abortion Analgesia Clinical Research

目的探讨联合用药用于人工流产镇痛效果。方法实验1组静脉缓慢推注丙泊酚2 mg/kg,2%利多卡因5 mL加阿托品1 mg,配制混合药液6 mL在暴露宫颈后将麻醉剂分点注射到宫颈周围。实验2组静脉缓慢推注丙泊酚2 mg/kg。对照组静脉推注生理盐水5 mL。所获数据采用x2和t检验。结果实验1、2组显效率为100%,与对照组比较P<0.01;实验1组宫颈完全松弛和较松弛达74.2%,实验2组为46.7%,两组比较有差异非常显著性(P<0.01)。对照组为45.8%,实验2组与对照组比较差异无显著性(P>0.05)。术中轻度呼吸抑制发生率、明显呼吸抑制发生率,实验2组显著高于实验1组(P<0.05)。结论丙泊酚联合利多卡因、阿托品用于无痛人工流产,具有镇痛效果好、宫颈内口扩张充分、手术时间短、用药量小、费用低并可减少呼吸抑制及人工流产综合征的发生率,是安全有效的镇痛方法。

Objective To investigate the propofol combined analgesic effect of lidocaine and atropine used for induced abortion. Methods Experimental group 1 vein slowly push propofol injection mg/kg, 2% lidocaine 5 ml and atro- pine 1 mg, confecting blended 6 ml of liquids. After the cervix. Experiment 2 groups vein slowly push propofol injection mg/kg. The control group intravenous saline injection 5 ml. The data obtained by chi-square and t test. Results The experimental group 1 and 2 show the efficiency of 100%, compared with control group （P〈0.01）. Experiment 1 set of cervical total relaxation and a relaxation of 74.2%, experimental group was 46.7%, 2 are similar between the two groups was very significant （P〈0.01）. Control group was 45.8%, and the experiment 2 groups there was no significant difference compared with control group （P〉0.05）. Intraoperative mild respiratory depression incidence, the incidence of respiratory depression, experimental group is significantly higher than the experiment 1 group 2 （P〈0.05）. Conclusion Propofol combined of lidocaine and atropine used in painless induced abortion, has good effect of analgesia, intracervical mouth expansion fully, shorter operation time, small dose, low cost and can reduce the incidence of respiratory depression and artificial abortion syndrome, etc, is safe and effective analgesic method.