丹参酮预防产后血栓形成的研究

The Study on How to Prevent to Form Thromboembolism after Delivery Treated with Tanshinone

目的探讨血浆D-二聚体测定联合丹参酮预防产后血栓栓塞性疾病的疗效。方法 2130例产妇随机分为两组研究组和对照组,各1065例。两组又分别分出自然分娩和剖宫产组。研究组产妇根据血浆D-二聚体水平预防应用丹参酮,观察两组产妇下肢静脉血栓、肺栓塞、脑栓塞及产后出血的发生情况。结果研究组下肢静脉血栓、肺栓塞及脑栓塞的发生显著低于对照组(P值均<0.01),两组产后出血差异无显著性差异(P>0.05)。结论测定血浆D-二聚体值并联合应用丹参酮可有效预防产后血栓栓塞性疾病的发生。

Objective To explore determination of plasma D - dimer combined the curative effect of tanshinone to prevent postpartum thromboembolic disorders. Methods 2130 cases of puerpera were randomly divided into research group and the control group, 1065 cases in each group. In the two groups respectively to separate natural birth and cesarean delivery group. The research group preventive applicated of tanshinone, according to the level of plasma D - dimer mater- nal. To observe two groups of maternal vein thrombosis of lower limb, pulmonary embolism, cerebral embolism, and the occurrence of postpartum hemorrhage. Results The group of lower limb venous thrombosis and pulmonary embolism and cerebral embolism was significantly lower than the control group （P value is less than 0.01）, postpartum hemorrhage similar between the two groups has no statistical significance （P〉0.05）. Conclusion The determination of plasma D - dimer values and combined use of tanshinone can effectively prevent the occurrence of postpartum thromboembolic disorders.