ATP对阵发性心房颤动环肺静脉电隔离术后疗效判断的价值

Effects of Adenosine Triphosphate on Recovered Left Atrium-pulmonary Veins Conduction after Circumferential Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation

目的探讨三磷酸腺苷(ATP)对阵发性心房颤动患者环肺静脉电隔离(CPVI)术后左房-肺静脉电传导恢复的影响。方法 75例阵发性心房颤动患者在完成消融术后两次给予三磷酸腺苷诱导肺静脉电传导恢复,对肺静脉电位恢复者补充消融重新到达肺静脉隔离。另有对照组84例阵发性心房颤动患者常规完成消融术后不做诱导试验。比较两组患者心房颤动术后复发率。结果试验组心房颤动复发率21.33%,对照组心房颤动复发率30.95%,差异有统计学意义(P<0.05)。结论补充消融三磷酸腺苷"暴露"的肺静脉电传导间隙,可减少阵发性心房颤动的复发率。

Objective To explore the effects of adenosine triphosphate on recovered left atrium_pulmonary veins conduction after cir-cumferential pulmonary vein isolation （CPVI） for paroxysmal atrial fibrillation.Methods Adenosine triphosphate was injected twice to 75 patients with paroxysmal atrial fibrillation after CPVI in order to induce pulmonary vein conduction recovery.If pulmonary vein po-tential had recovered ,ablation was carried out to reach pulmonary vein isolation again .84 patients with paroxysmal atrial fibrillation after CPVI considered as control group had not been induced.Recurrence rate of atrial fibrillation of two groups were compared.Re-sults Recurrence rates of atrial fibrillation of test group and control group were 21.33% and 30.95% respectively （ P〈0.05）.Con-clusions Additional ablation for ATP_induced pulmonary vein conduction gaps after CPVI can reduce recurrence rate of paroxysmal a-trial fibrillation.