益气化瘀方治疗2型糖尿病下肢动脉闭塞临床观察

Clinical observation of “Yiqi Huayu Decoction ” for the treatment of type 2 diabetic arterial occlusion of lower extremities

目的观察益气化瘀方治疗2型糖尿病下肢动脉闭塞症(DAO)的临床疗效。方法将60例DAO患者随机分为治疗组和对照组,各30例;两组均给予常规西药治疗以控制血糖,治疗组同时服用益气化瘀方,疗程12周。治疗前后分别用多普勒超声检测患者下肢动脉内径和收缩期最大血流速度。结果治疗后两组患者下肢各动脉内径均较治疗前明显增宽(P<0.05),且治疗组各动脉内径较对照组增宽(P<0.05);两组患者下肢各动脉血流速度均较治疗前明显增快(P<0.05),且治疗组各动脉血流速度较对照组增快(P<0.05)。结论益气化瘀方能明显改善2型糖尿病患者下肢动脉硬化闭塞症。

Objective To observe the clinical efficacy of ＂ Yiqi Huayn Decoction＂ in the treatment of type 2 diabetic arterial occlusion （DAO） of lower extremities. Methods Sixty cases with DAO were randomized into treatment group and control group, with 30 cases in each group. Both of the groups were treated by conventional western medicine to control blood glucose. Additionally, treatment group was treated with ＂ Yiqi Huayu Decoction＂, with the course of 12 weeks. The inner diameter and maximum blood flow velocity of lower extremity vessels were detected by color Doppler image before and after treatment. Results After treatment, the inner diameter of lower extremity vessels were obviously dilated in both groups （ P 〈 0.05 ）, with more significant dilation in the treatment group than that of the control group （ P 〈 0.05 ）. After＂ treatment, the blood flow velocity increased obviously in both groups （ P 〈 0.05 ）, with significant difference between the two groups （ P 〈 0.05 ）. Conclusion ＂Yiqi Huayu Decoction＂ is effective for type 2 diabetic arterial occlusion of lower extremities.