肿瘤靶向治疗药物载体的研究进展

Research progress on anti-tumor targeting drug carriers

传统抗肿瘤药物最大的治疗缺陷是药物作用多是非选择性的,在杀伤癌细胞的同时,对正常组织产生较强的毒副作用。因此针对癌组织的肿瘤靶向治疗成为国内外研究的热点,目前采用靶向性强的药物载体来提高抗肿瘤药物的有效利用率取得了不错的研究进展。本文就靶向制剂设计模式、靶向治疗药物载体系统、靶向药物载体的研究现状进行了的综述。

The maximum deficiency of traditional anti - tumor drugs is not selective. The drugs not only kill tumor cells,but also cause damage to normal tissues. Therefore,the present research focuses on tumor - targeting therapies,and the strategy of adopting tar-geting drug carriers to increase the efficiency of anti - tumor drugs has made progress. The design patterns of targeting anti - tumor drugs,the drug carrier systems and current advance of drug carriers were discussed in this paper.