不同速度的恒速输注方式与靶控输注方式输注丙泊酚对老年患者全麻诱导插管过程中生命体征的影响

Affect on vital signs of constant rate infusion at different speeds and target controlled infusion of propofol in elderly patients during general anesthesia intubation induction process

目的探讨不同速度的恒速输注方式与靶控输注方式输注丙泊酚对老年患者全麻诱导插管过程中生命体征的影响。方法选择60例老年择期行全麻手术患者,按入院顺序随机分为两组,每组30例,对照组患者使用靶控输注方式输注丙泊酚进行麻醉,研究组患者使用不同速度的恒速输注方式输注丙泊酚进行麻醉。比较两组患者血流动力学变化情况及诱导过程和插管过程血压变化情况。结果研究组患者血流动力学波动较对照组平稳,对照组插管前(T1)、插管即刻(T2),插管5 min后(T3)较麻醉诱导前及研究组变化明显,比较差异具有统计学意义(P<0.05);对照组患者麻醉诱导及插管过程中血压改变过30%共21例,明显高于研究组5例,比较差异具有统计学意义(P<0.05)。结论不同速度的恒速输注方式输注丙泊酚对老年患者进行全麻诱导时,对其心脑血管等抑制作用较小,操作简单易控制,值得临床推广应用。

Objective To evaluate the affect on vital signs of constant rate infusion at different speeds and target controlled infusion of propofol in elderly patients during general anesthesia intubation induction process. Methods 60 cases of elderly patients was performed anesthesia for elective surgery in our hospital. All these patients were randomly divided into two groups according to the order of admission of 30 patients. The control group of patients used target-controlled infusion propofol anesthesia while the study group patients used different speeds constant rate infu-sion of propofol anesthesia. To compare hemodynamic change,blood pressure change during induction intubation process. Results The study group had a stable hemodynamic change. The control group before intubation（T1）,intubation（T2）,5min after intubation（T3）had a signifi-cant change when compared with before induction of anesthesia and the study group. The difference was statistically significant（ P 〈0. 05）. The blood pressure of 21 cases of the control group patients＇ changed over 30% during the induction of anesthesia and intubation,which was significant-ly higher than 5 cases of the study group. The difference was statistically significant（ P 〈0. 05）. Conclusion Constant infusion at different speeds of propofol induction of anesthesia in elderly patients has a small inhibition in cardiovascular. This method is simple and easy to control, which is worthy of clinical application.