阳中求阴法治疗干燥综合征50例临床观察

Clinical observation of seeking Yang in Yin method on Sjogren's syndrome

目的观察阳中求阴法治疗干燥综合征的临床疗效。方法将100例干燥综合征患者随机分为2组,对照组50例予中西医结合常规治疗,治疗组50例在对照组中药方中加桂枝6 g、炮姜10 g。2组均1个月为1个疗程,3个疗程后统计疗效,观察2组治疗前后中医症状积分、红细胞沉降率、唾液流率、C反应蛋白及免疫球蛋白变化。结果与对照组比较,治疗组临床疗效优于对照组(P<0.05),中医症状改善明显(P<0.05),红细胞沉降率、C反应蛋白、免疫球蛋白下降(P<0.05),唾液流率升高(P<0.05)。结论阳中求阴法可明显改善干燥综合征中医临床症状,疗效确切。

Objective To observe the effect of seeking Yang in Yin method on Sjogren＇s syndrome . Methods 100 patients with Sjogren＇s syndrome were randomly divided into two groups .50 patients in control group were treated by conventional therapy of integrated Chinese and Western medicines .50 cases in treatment group additionally received Cassia Twig , 6 g and common ginger , 10 g on the basis of control group treatment .The course was a month in two groups .The curative rate was evaluated after three courses .The changes of traditional Chinese medicine symptoms score , erythrocyte sedimentation rate , saliva flow rate , C -reactive protein and the immun-oglobulin were observed .Results Compared with those in control group , the curative effect in treatment group was better （ P 〈0.05 ）, the improvement of traditional Chinese medicine symptoms was more obvious （P〈0.05）, Erythrocyte sedimentation rate, C-reactive protein and the immunoglobulin was decreased （P〈0.05）, saliva flow rate was increased （P〈0.05）.Conclusion Seeking Yang in Yin method can significantly improve clinical symptoms of Sjogren＇s syndrome and has the exact effect .