雷公藤多苷片治疗临床蛋白尿期糖尿病肾病的疗效与安全性

目的观察分析雷公藤多苷片治疗临床蛋白尿期糖尿病肾病的疗效与安全性。方法对江西省泰和县人民医院收治的76例处于临床蛋白尿期糖尿病肾病患者,按照治疗方法的不同划分为2组,对照组42例接受科素亚治疗,观察组34例接受雷公藤多苷片治疗,对比观察2组治疗效果。结果 76例患者中,观察组治疗总有效率为94.1%,对照组治疗总有效率为76.2%,差异有统计学意义(P<0.05),2组均无明显不良反应,观察组患者的复发率(2.9%)显著低于对照组(21.4%),差异有统计学意义(P<0.05)。结论采用雷公藤多苷片治疗临床蛋白尿期糖尿病肾病,疗效显著,安全可靠,值得应用推广于临床治疗中。

Objective To observe the clinical analysis of tripterygium wilfordii glycosides tablets more treatment the curative effect and security of the diabetic nephropathy proteinuria. Methods 76 cases of Jiangxi province people’s hospital in phase clinical albuminuria in patients with diabetic nephropathy, according to the different method of treatment is divided into two groups, control group of 42 patients treated for a division, the observation group of 34 patients treated with tripterygium wilfordii glycosides tablets more, compared two groups of therapeutic effect. Results 76 cases of patients, the observation group treatment the total effective rate was 94.1%, control group total effective rate was 76.2%, the difference was statistically significant （P＆lt;0.05）, two groups had no obvious adverse reaction, observation group of patients with recurrence rate（2.9%） was significantly lower than the control group（14.3%）,the difference was statistically significant （P＆lt;0.05）. Conclusion Using tripterygium wilfordii glycosides tablets to treat more clinical proteinuria stage of diabetic nephropathy, curative effect is distinct, safe and reliable, and is worth popularizing application in clinical treatment.