惠州地区复发性外阴阴道念珠菌病复发因素分析

Analysis of the Relapse Factors of Recurrent Vulvovaginal Candidiasis in Huizhou Region

目的:探讨复发性外阴阴道念珠菌病(RVVC)病情复发因素。方法:选取确诊为RVVC的患者50例和初次或偶发的外阴阴道念珠菌病(VVC)患者50例,分别对两组患者发病前15项生活和生理状况进行调查对比分析。结果:RVVC组排在前5位的因素依次为:发病前5 d内性生活、生理状况差、心理负面情绪、月经来潮和性伴同患生殖器念珠菌病;在生理状况差、心理负面情绪、月经来潮、性伴同患生殖器念珠菌病和性生活频率(≥3次)5个因素,两组间比较差异有统计学意义(P<0.05),其余因素在两组间无明显差异(P>0.05)。结论:RVVC患者病情复发与发病前5 d内性生活、生理状况差、心理负面情绪、月经来潮和性伴同患生殖器念珠菌病有明显关系。

Objective： To explore the relapse factors of recurrent vulvovaginal eandidiasis （ RVVC ） .Method： 50 patients were diagnosed RVVC and 50 patients with initial or occasional vulvovaginal candidiasis （ VVC ） were included. 15 items of factors about the lifestyle and the physiological status before the onset of disease were analyzed between the two groups respectively. Result： The top five factors in RVVC group were： sexual activity within 5 days before the onset of disease, poor physical condition, mental negative emotions, menstrual onset and partners with genital candidiasis. There were the significant difference between the two groups in 5 factors ： poor physical condition, mental negative emotions, menstrual cramps, partner with genital candidiasis and frequency of sexual activity （ ≥ 3 times ） （ P〈0.05 ）, and the remaining factors had no significant difference between the two groups （ P〉0.05 ） . Conclusion： The relapse of RVVC has a significant relationship with sexual activity within 5 days before the onset of disease, poor physical condition, mental negative emotions, menstrual onset and partners with genital candidiasis.