老年血吸虫肝病合并胆囊疾病的影响因素

Influencing factors in elderly patients with schistosomiasis liver disease combined with gallbladder diseases

目的了解老年血吸虫肝病患者合并胆囊疾病状况,探讨血吸虫肝病合并胆囊疾病的影响因素。方法 280例老年血吸虫肝病患者分为2组,慢性肝纤维化组198例,肝硬化组82例,对胆囊B超检查结果及肝功能回顾性分析,进行统计学处理。结果 280例老年血吸虫肝病患者中,合并胆囊疾病者157例,占56.1%。其中胆囊壁增厚为28.2%(79/280),胆结石为13.6%(38/280),胆囊炎为11.1%(31/280),胆囊息肉为3.2%(9/280)。血吸虫肝病肝硬化组患者胆囊壁增厚、胆囊炎、胆结石的发病率较纤维化组明显增高,2组差异有统计学意义(χ2=4.568,P<0.05)。结论老年血吸虫病患者合并胆囊疾病的主要影响因素为年龄、病程、肝硬化及门脉高压程度。

Objective To understand the status of elderly patients with schistosomiasis liver diseases combined with gallblad-der diseases,and explore the influencing factors. Methods A total of 280 elderly patients with schistosomiasis liver disease were divided into two groups,198 cases of chronic liver fibrosis and 82 cases of liver cirrhosis,and the results of their gallbladder ultra-sound and liver function examinations were analyzed statistically. Results Among the 280 cases,157 patients were combined with gallbladder diseases（56.1%）,including gallbladder wall thickening（28.2%,79/280）,cholecystolithiasis（13.6%,38/280）,cholecystitis（11.1%,31/280）,and gallbladder polyp（3.2%,9/280）. The incidence rates of gallbladder wall thickening, cholecystitis and cholecystolithiasis in the schistosomiasis patients with cirrhosis were significantly higher than those in the schisto-somiasis patients with liver fibrosis（χ2=4.568,P＆lt;0.05）. Conclusion The main influencing factors of schistosomiasis liver dis-ease combined with gallbladder diseases are the age,the course of the disease,liver cirrhosis and the portal hypertension degree.