轻微型肝性脑病诊断研究进展

Diagnosis of minimal hepatic encephalopathy

轻微型肝性脑病常并发于肝硬化及各种门体分流术患者。由于缺乏典型的临床表现及生化异常，只能通过心理智能测试及神经电生理等检查发现，其发病率已升至30%～84%。轻微型肝性脑病可对患者的日常生活造成影响，无干预的轻微型肝性脑病易发展为显性肝性脑病。该病尚无公认的诊断“金标准”。本文介绍了国内外对轻微型肝性脑病的诊断方法。

Minimal hepatic encephalopathy （MHE） is a common complication of decompensated liver cirrhosis or in pa-tients with various portal-systemic shunt. Due to lack of typical clinical features and biochemical abnormally, MHE can only be diagnosed through psychometric or neurophysiological tests. And its incidence has increased to 30% to 84%. MHE affects daily life of patients, and it may make progress to overt hepatic encephalopathy without intervention. So far, there is no well estab-lished method to define its diagnosis as golden standard. This review mainly introduces the diagnostic methods applied at home and abroad.