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老年危重症患者血清维生素D水平与APACHEⅡ评分和预后的相关性分析 被引量:1

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摘要 目的探讨老年危重患者血清1,25羟-维生素D3[1,25(OH)2D3]水平与急性生理功能和慢性健康状态Ⅱ(APACHEⅡ)评分及预后的相关性。方法将196例老年危重患者按APACHEⅡ评分分为A组(APACHE1I≤15)、B组(16≤APACHE1I≤25)和C组(APACHE1I>25),根据转归分为死亡组与存活组,分析APACHE1I评分与血清1,25(OH)2D3及院内死亡率的相关性。结果 A组血清1,25(OH)2D3水平和院内病死率与B组和C组差异均有统计学意义(均<0.05);B组血清1,25(OH)2D3水平和院内病死率与C组差异均有统计学意义(均<0.05)。存活组血清1,25(OH)2D3水平明显高于死亡组(<0.01),血清1,25(OH)2D3水平与APACHEⅡ评分呈负相关(=-0.458,<0.05),与院内病死率呈负相关(=-0.871,<0.05)。结论老年危重患者血清1,25(OH)2D3水平低下提示病情危重且不良预后可能性增加。
机构地区 上虞市中医院
出处 《现代实用医学》 2014年第4期490-491,共2页 Modern Practical Medicine
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