颅脑外科手术前服用阿司匹林与术后颅内出血的相关性研究

Association between postoperative intracranial hemorrhage and aspirin administration before craniotomy

目的探讨术前服用阿司匹林与颅脑手术后出血的相关性。方法选择2010年4月至2011年4月在我院接受颅脑外科手术患者158例,分为服用阿司匹林组(58例)和未服用阿司匹林组(100例),服用阿司匹林患者术前停药2周后手术。结果服用阿司匹林组术后发生出血仅1例,未服用阿司匹林组无术后出血,差异无统计学意义。结论服用阿司匹林术前停药2周后手术是安全可靠的。

Objective To study the association between postoperative intracranial hemorrhage and aspirin administration before craniotomy. Methods One hundred and fifty-eight patients who received craniotomy during April 2010 to April 2011 were divided into two groups： 58 cases taking aspirin and 100 cases without aspirin administration. The former group stopped aspirin 2 weeks before surgery. Results Only one patient in the taking aspirin group had postoperative intracranial hemorrhage. Patients without aspirin administration had no intracranial hemorrhage. There was no statistics significant difference between the two groups. Conclusion Cranioecetomy is save if patients stop taking aspirin 2 weeks before operation.