615例宫颈液基薄层细胞学临床应用研究

The chincal application study of 615 cases cervical ThinPrep cytology

目的:通过对高校女教职工宫颈液基薄层细胞学检查(TCT)结果分析,了解该群体宫颈病变的发生情况以及TCT的临床应用价值和意义。方法:采用TCT法,对我校615名年龄在20～76岁女教职工体检者进行筛查,以病理组织学检查作为评价和诊断标准。结果:TCT检测与病理组织学检查比对检出符合率高,而且病理级别越高,符合率越高。ASC-H符合率为66.67%、LSIL符合率为87.50%,HSIL、SCC的符合率为100%。在宫颈病变各年龄组构成比分析中,高校女教职工在40～49岁年龄组患病较高,各年龄组构成依次为3.45%、4.89%、10.32%、2.56%,经统计学分析40～49岁组与各年龄组比较有显著性差异(P<0.05)。结论:TCT宫颈检查法对宫颈病变的筛查具有重要的临床应用价值和意义,值得推广。

Objective：To discuss the occurrence of cervical lesions by means of analysis based on 615 subjects of the university female staff of Thinprep Cytologic Test （TCT）. Methods：Using TCT method,615 students in our university at the age of 20-76 years old female staff physical examination for screening , the histopathological examination as the evaluation and diagnostic criteria . Results：TCT detection and pathological examination on the coincidence rate is high,and the pathological grades higher,the coincidence rate is higher. ASC-H coincidence rate was 66.67%, LSIL coincidence rate was 87.50%,HSIL,SCC with the rate of 100%. In cervical lesions in each age group in constituent ratio analysis,the university female staff higher prevalence in the 40 to 49 age group,each age group were 3.45%,4.89%,10.32%,2.56%,the statistical analysis 40-49 years old group and each age group were significantly different（P〈0.05）. Conclusion：Clinical significance of TCT examination of cervical screening results of cervical lesions, worthy of promotion.