期刊文献+

噻托溴铵在支气管哮喘治疗中的地位 被引量:16

原文传递
导出
摘要 支气管哮喘(简称哮喘)是一种慢性呼吸道疾病,表现为继发于过敏性炎症和支气管平滑肌过度收缩导致的可逆性气道阻塞[1].目前,基于对哮喘发病机制的认识,抗炎药物[主要是吸入型糖皮质激素(ICS)]和支气管扩张剂[主要是吸入长效β2激动剂(LABA)]已被广泛地用于哮喘的治疗.
作者 王雯 施焕中
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第16期1207-1208,共2页 National Medical Journal of China
  • 相关文献

参考文献10

  • 1The Global Initiative for Asthma. Pocket Guide for Asthma Management and Prevention. Updated 2013 [ S/OL]. [ 2014-03- 01 ]. http://www, ginasthma, org/guidelines-poeket-guide- for- asthmamanagement, htrnl.
  • 2Ohta S, Oda N, Yoke T, et al. Effect of tiotropium bromide on airway inflammation and remodeling in a mouse model of asthma [J]. Clin Exp Allergy, 2010, 40: 1266-1275.
  • 3Gross NJ. Tiotropium bromide [ J]. Chest, 2004, 126: 1946- 1953.
  • 4Ohta S, Oda N, Yoke T, et al. Effect of tiotropium bromide on airway inflammation and remodeling in a mouse model of asthma [J]. Clin Exp Allergy, 2010,40: 1266-1275.
  • 5Buels KS, Jacoby DB, Fryer AD. Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma[ J]. Br J Pharmacol, 2012, 165 : 1501-1514.
  • 6Park HW, Yang MS, Park CS, et al. Additive role of tiotropium in severe asthmatics and Argl6Gly in ADRB2 as a potential marker to predict response [ J ]. Allergy, 2009, 64 : 778-783.
  • 7Terzano C, Petroianni A, Ricci A, et al. Early protective effects of tiotropium bromide in patients with airways h [ J]. Eur Rev Med Pharmacol Sci, 2004, 8 : 259-264.
  • 8Peters SP, Kunselman SJ, Icitovic N, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma[ J]. N Engl J Med, 2010, 363: 1715-1726.
  • 9Kerstjens HA, Disse B, SchrSder-Babo W, et al. Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trim [ J ]. J Allergy Clin Immunol, 2011, 128: 308-314.
  • 10Bateman ED, Kornmann O, Schmidt P, et al. Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma [J]. J Allergy Clin Immunol, 2011, 128: 315-322.

同被引文献145

  • 1郑英明,谢强敏.抗肿瘤坏死因子α用于重度哮喘治疗的研究进展[J].世界临床药物,2009,30(12):757-760. 被引量:2
  • 2艾强,张江宇.噻托溴铵对比于异丙托溴铵治疗慢性阻塞性肺疾病的系统评价[J].中华临床医师杂志(电子版),2011,5(21):6363-6367. 被引量:6
  • 3谢桃,李国平.氧化应激与支气管哮喘气道黏液高分泌研究进展[J].中华哮喘杂志(电子版),2013,7(1):49-52. 被引量:4
  • 4俞峰,周林福.氨茶碱和多索茶碱治疗支气管哮喘的临床疗效比较[J].中国生化药物杂志,2014,34(6):8-10. 被引量:87
  • 5Yick CY,AH,Zwinderman PW, Kunst,et al. Glucocorticoid -induced changes in gene expression of airway smooth muscle inpatients with asthma [ J ]. American journal of respiratory andcritical care medicine,2013 ,187( 10) : 1076-1084.
  • 6Green BJ,Wiriyachaiporn S,Grainge C,et al.Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma. PLo S One . 2014
  • 7Sha lieva LO,Fedoseev GB,Zorina ML,et al.Clinical,laboratory,and functional characteristic of patients with bronchial asthma and chronic obstructive pulmonary disease with disturbances of oxalic acid metabolism. Klinicheskaia meditsina . 2013
  • 8ZHANG Y L,LUAN B,WANG X F,et al.Peripheral blood MDSCs,IL-10and IL-12in children with asthma and their importance in asthma development. PLoS One . 2013
  • 9Fruchter O,Kramer MR.Bronchial thermoplasty-a novel method for the treatment of severe asthma. Handchirurgie Mikrochirurgie Plastische Chirurgie . 2014
  • 10Novelli F,Costa F,Latorre M,et al.Tiotropium:a new therapeutic option in asthma. Monaldi Archives for Chest Diseases Cardiac Series . 2013

引证文献16

二级引证文献149

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部