期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

代谢型谷氨酸受体调节剂在颅脑损伤后的应用 被引量：3

Application of metabotropic glutamate receptor modulators after brain injury
下载PDF
导出
摘要 颅脑损伤(TBI)是现代社会中的一个突出问题,以其致残率和致死率高、社会危害性大等原因,一直备受创伤学界的关注。本文对继发性颅脑损伤的机制及代谢型谷氨酸受体调节剂在伤后的应用进行了综述。 Traumatic brain injury （ TBI） is a prominent issue in modern society ,which has high morbidity and mortality ,and social harmness ,has received high traumatic academic attention .In this paper ,the mechanism of secondary brain injury and the application of metabotropic glutamate receptor modulators after injury were reviewed .
作者 朱星全 许民辉 王昊
机构地区 第三军医大学第三附属医院神经外科
出处 《创伤外科杂志》 2014年第3期270-272,共3页 Journal of Traumatic Surgery
关键词 颅脑损伤 神经保护 调节剂 brain injury neuroprotection modulators
分类号 R651.1 [医药卫生—外科学]
  • 相关文献

参考文献2

二级参考文献11

  • 1王过渡,卓敏.成年小鼠前脑NMDA受体参与神经元的动作电位发放(英文)[J].生理学报,2006,58(6):511-520. 被引量：3
  • 2Bullock R. Excitatory amino acids following brain injury [J]. J Neurosurg, 1994, 80 : 595-596.
  • 3Bullock R, Zauner A, Woodward JJ, et al. Factors affecting excitatory amino acid release following severe human head injury [J]. J Neurosurg, 1998, 89: 507-518.
  • 4Foda MA, Marmarou A. A new model of diffuse brain injury in rats [J]. J Neurosurg, 1994, 80: 301-13.
  • 5Humm JL, Kozlowski DA, Bland ST, et al. Use-dependent exaggeration of brain injury: is glutamate involved [J]? Exp Neurol, 1999, 157: 349-358.
  • 6Monyer H, Giffard RG, Hartley DM, et al. Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin [J]. Neuron, 1992, 8: 967-973.
  • 7McDonald JW, Fix AS, Tizzano JP, et al. Seizures and brain injury in neonatal rats induced by 1s, 3g-ACPD, ametabotropic glutamate receptor agonist [J]. J Neurosci, 1993, 13: 4445-4455.
  • 8Nicoletti F, Bruno V, Copani A, et al. Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders [J]. Trends Neurosci, 1996, 19: 267-271.
  • 9Opitz T, Richter P, Reymann KG. The metabotropic glutamate receptor antagonist(α-methyl-4-carboxyphenylglycine) protects hippocampal CA1neurons of the rat from in vitro hypoxia / hypoglycemia [J]. Neuropharmacology, 1994, 33:715-717.
  • 10Fei Zhou, Zhang Xiang, Lu Peiling, et al. The expression and changes of heat shock protein 70, MDA and hemorheology in rat cortex after diffuse axonal injury with secondary insults [J]. J Clin Neurosci, 2001, 8 : 250-252.

共引文献26

同被引文献29

  • 1疏树华,方才.兴奋性氨基酸及受体与脑损伤的研究进展[J].立体定向和功能性神经外科杂志,2007,20(2):124-126. 被引量：26
  • 2Marmarou A,Foda MA,van den Brink W,et al.A new model of diffuse brain injury in rats. Part I. Pathophysiology and biomechamics[J].J Neurosurg, 1994,80(2) : 291 -- 230.
  • 3Hewlett KA, Corbett D..Delayed minocycline treatment reduces long term functional deficits and histological injury in a rodent model of focal ischemia[J]. Neuroscience, 2006,141 (1) :27--33.
  • 4Nikodemova M, Watters JJ, Jackson SJ, et al. Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC) a/13 ]I [J].J Biol Chem,2007,282(20) : 15208--15216.
  • 5Pabreja K, Dua K ,Sharma S, et al.Minocycline attenuates the development of diabetic neuropathic pain: possible anti- inflammatory and anti-oxidant mechanisms [J]. Eur J Pharmacol, 2011,661(1) : 15--21.
  • 6Willard SS, Koochekpour S.Glutamate, glutamate receptors, and downstream signaling pathways[J].Int J Biol Sci,2013,9 (9) :948--959.
  • 7Tymianski M, Charhon MP, Carlen PL, et al. Sourcespecificity of early calcium neurotoxicity in cultured embryonic spinal neurons [ J ]. J Neurosci, 1993, 13 ( 5 ) : 2085--2104.
  • 8盛鹏杰,主编.缺血性脑血管病[M]. 中国医药科技出版社, 2009
  • 9Satoshi Terao,Gokhan Yilmaz,Karen Y. Stokes,Mami Ishikawa,Takeshi Kawase,D Neil Granger.Inflammatory and Injury Responses to Ischemic Stroke in Obese Mice[J].Stroke.2008(3)
  • 10陈廷福,金先庆,杨坤,赵丽华.丙泊酚、神经节苷脂对幼鼠认知和caspase-3表达的影响[J].解放军医学杂志,2010,35(7):845-848. 被引量：10

引证文献3

二级引证文献6

创伤外科杂志
2014年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部