谷氨酰胺强化肠内营养治疗非感染性腹泻临床疗效分析

Clinical Curative Effect Analysis of Glutamine Enhanced Enteral Nutrition Treatment for Non-infectious Diarrhea

目的观察谷氨酰胺强化肠内营养治疗非感染性腹泻的临床疗效.方法将2011年3月至2013年3月玉溪市人民医院收治的90例非感染性腹泻患者随机分为谷氨酰胺治疗的治疗组和思密达治疗的对照组,治疗组43例,对照组47例,治疗6周后观察疗效及相关指标情况,并对研究数据进行统计分析比较.结果治疗组在腹痛、腹泻控制时间方面优于对照组,在治疗总有效率上,治疗组总有效率为88.3%,对照组总有效率74.4%,2组差异有统计学意义(P<0.01),电子肠镜观察肠内形态、不良反应及随访6周是否复发的结果方面,治疗组均优于对照组(P<0.01).结论谷氨酰胺治疗非感染性腹泻临床应用疗效确切,值得临床推广.

Objective The purpose of this study was to observe the clinical curative effect of glutamine enhanced enteral nutrition therapy for non-infectious diarrhea.Methods 90 patients with non-infectious diarrhea were randomly divided into the treatment group （43 cases） by glutamine therapy and the control group （47 cases）by smecta from March 2011 to March 2013 in our hospital.The curative effect and the related indicators were observed after six weeks treatment.Results The abdominal pain and diarrhea control time in treatment group were better than those in control group.The total effective rate in treatment and control groups was 88.3％ and 74.4％,respectively,and there was statistical difference between the two groups.The intestinal morphology,adverse reaction and recurrence cases during the 6 weeks follow-up in the treatment group were superior to the control group.Conclusion Glutamine treatment for non-infectious diarrhea is effective and worthy of clinical promotion.