纳米银敷料对Ⅱ°烧伤创面的疗效临床观察

Clinical Observation on Nano Silver Dressing for Ⅱ° Burn Wounds

目的探讨纳米银敷料与1%磺胺嘧啶银乳膏对烧伤创面的疗效评定.方法随机选择II°烧伤患者160例分组,1%磺胺嘧啶银乳膏组(A组)80例,纳米银敷料组(B组)80例,创面分别用药后,观察创面细菌检出率、愈合时间、发热情况、肝肾功毒副作用指标等.结果 A组与B组细菌培养阳性率比较,差异有统计学意义(P<0.01),创面愈合时间差异有统计学意义(P<0.01);发热例数差异有统计学意义(P<0.01);肝肾功能指标差异无统计学意义(P>0.05).结论纳米银敷料作为新一代医用抗感染敷料,能有效地抑制或杀灭烧伤创面病原菌,其创面抗感染效果、创面愈合时间均优于传统的1%磺胺嘧啶银乳膏,很大程度的降低了烧伤患者的感染率,减少了对抗生素的抵抗性与依赖性.

Objective To evaluate the curative effects of nano silver dressing and 1％ sulfadiazine silver cream on burn wounds.Methods After using burn wound medicine respectively to Ⅱ° burn patients 160 cases from which nano silver dressing group （group A）,80 cases,1％ sulfadiazine silver cream group 80 cases （group B） were classified,the indexes such as wound bacteria detection rate,healing time,fever,liver and kidney toxicity were observed.Results Group A and group B germiculture positive rate had significant differences （P＜ 0.01）.The wound healing time also had significant differences （P＜0.01）.Fever cases had statistical significance （P＜0.01）.There was no significant difference between liver and kidney function index.Concltsion As a new generation medical dressing,Nano silver dressing has good effectiveness in inhibiting or killing pathogen in burn wounds,its anti-infective effects and wound healing time are better than the traditional 1％ sulfadiazine silver cream,meanwhile it also plays a great role in decreasing the infection rate of burn patients,reducing the resistance and dependence to antibiotics.