垂体后叶素在腹腔镜子宫肌瘤剔除术中应用的临床分析

THE CLINICAL APPLICATION OF PITUITRIN IN LAPAROSCOPIC MYOMECTOMY

目的探讨垂体后叶素在腹腔镜子宫肌瘤剔除术中应用的安全性及可行性。方法选择2011年1月—2013年12月在攀枝花市第六人民医院术前诊断子宫肌瘤及有保留子宫要求的患者95例。随机分为观察组48例,对照组47例。二组患者均行腹腔镜下子宫肌瘤剔除术。观察组术中于子宫肌瘤周围肌层注入垂体后叶素,对照组术中于子宫肌瘤周围肌层注入缩宫素。比较二组手术时间、术中出血量、术后排气时间、用药前后血压波动情况。结果观察组手术时间显著少于对照组,观察组出血量显著少于对照组,术后排气时间显著短于对照组,且P值均<0.05,差异具有统计学意义。二组用药前后血压波动无明显差异。结论垂体后叶素应用于腹腔镜子宫肌瘤剔除可以显著减少出血量,缩短手术时间,缩短术后排气时间,减低手术难度、操作简单,方便经济,有十分肯定的效果,值得临床广泛推广应用。

Objective To investigate the safety and feasibility of pituitrin in treatment of laparoscopic myonectomy. Methods Totally 95 patients diagnosed with uterine leiomyoma preoperatively and uterus fetalning requirements from January 2011 to December 2013 in author＇s department were selected, they were randomly divided into observation group（48 cases） and control group （47 cases）, and all patients underwent laparoscopic myomectomy. Observation group was in uterine fibroids peripheral muscular injection of pituitrin, the control group was in uterine fibroids peripheral muscle injection of oxytoein. The operation time, bleeding volume, postoperative exhaust time and blood pressure fluctuations were compared between the two groups. Results The operation time, amount of bleeding, postoperative exhaust time in observation group were significantly less than that in control group （P〈0.05）. Fluctuations in blood pressure had no significant difference in two groups before and after treatment. Conclusions Pituitrin used in laparoscopic myomectomy can significantly reduce the amount of bleeding, shorten operation time, reduce postoperative exhaust time, reduce the difficulty of operation, simple operation. It is worthy of extensive promotion and application with convenient and economic and a very positive effect in clinic.