宝鸡地区宫颈癌筛查方案的可行性研究

FEASIBILITY STUDY ON SCREENING PROGRAM OF CERVICAL CANCER IN BAOJI AREA

目的探讨宝鸡地区宫颈癌筛查方案的可行性。方法收集分析2010年1月—2013年11月在宝鸡市妇幼保健院进行宫颈癌筛查的患者资料,筛查方法包括巴氏细胞学、液基细胞学、高危型HPV检测,多功能醋酸白肉眼检测法,并经阴道镜检查,病理确诊宫颈癌及癌前病变。结果共筛查89 714例,其中组织性筛查59 745例,机会性筛查29 969例,筛查方法依次为巴氏细胞学69 285例,液基细胞学16 114例,HPV检测625例,多功能醋酸白肉眼检测3 604例。最常用的筛查方案是细胞学检查占95.19%。组织性筛查检出宫宫颈癌前病变(CINⅠ+CINⅡ+CINⅢ)916例(1.53%),宫颈癌96例(0.16%),机会性筛查检出颈癌前病变(CINⅠ+CINⅡ+CINⅢ)892例(2.98%),宫颈癌159例(0.53%)。结论巴氏细胞学仍为经济欠发达地区主要的宫颈癌筛查方法,机会性筛查宫颈病变检出率高,但仍不能忽视组织性筛查。

Objective To investigate the feasibility of screening program of cervical cancer in Baoji. Methods The data of screening for cervical cancer in Baoji Maternal and Child Health Hospital from January 2010 to November 2013 were collected and analyzed. Screening methods included Pap cytology, liquid based cylology, high- risk HPV detection, multi functional acetic acid test and the colposcopy examination, patho- logical diagnosis of cervical cancer and cancer precancerous lesions. Results A total of 89714 persons were screened, included 59745 cases of organized screening, 29969 cases of opportunistic screening. In the order, screening method was Pap cytology in 69285 cases, liquid based cytology in 16114 cases, HPV was detected in 625 cases and multiple functional acetic acid white test was performed by naked eye in 3604 cases. Cytology screening was most commonly accounted for 95.19M. A total of 916 cases （1. 530//00） of cervical precancerous lesions （CIN Ⅰ CIN Ⅱ CIN Ⅲ ） and 96 cases of cervical cancer （0.16%） were detected by organized screening, and 892 cases （2.98%） of cervical precancerous lesions （CIN Ⅰ CIN Ⅱ CIN Ⅲ） were found by opportunistic screening, at the same time, 159 cases of cervical cancer （0.53 %） were detected. Conclusions Pap cytology is the main approach for cervical cancer screening in underdeveloped areas, opportunistic screening for cervical lesion detection rate is high, but the organization screening still can not be ignored.